Benproperine MedChemExpress (MCE)

Product Name	benproperine phosphate
Synonyms	Blascorid ASA 158-5 243-050-0 Pirexyl phosphate benproperine phosphate BENPROPERINE PHOSPHATE BENPROPERINE PHOSPHATE CP2000 Synonyms Blascorid ASA 158-5 243-050-0 Pirexyl phosphate benproperine phosphate BENPROPERINE PHOSPHATE BENPROPERINE PHOSPHATE CP2000 Benproperine trihydrogen phosphate 1-[1-(2-benzylphenoxy)propan-2-yl]piperidine 1-(2-Benzylphenoxy)-2-piperidinopropane phosphate 1-(2-(2-Benzilfenossi)-1-metiletil)-piperidina fosfato 1-[2-(2-benzylphenoxy)-1-methylethyl]piperidine phosphate 1-(1-Methyl-2-(2-benzylphenoxy)ethyl)piperidine phosphate 1-[2-(2-Benzylphenoxy)-1-methylethyl]piperidine monophosphate 1-[2-(2-benzylphenoxy)-1-methyl-ethyl]piperidin-1-ium phosphate 1-(2-(2-Benzilfenossi)-1-metiletil)-piperidina fosfato [Italian] 1-(1-Methyl-2-((alpha-phenyl-o-tolyl)oxy)ethyl)piperidine phosphate 1-[2-(2-benzylphenoxy)-1-methylethyl]piperidinium dihydrogen phosphate 1-(2-(2-Benzylphenoxy)-1-methylethyl)piperidinium dihydrogen phosphate Piperidine, 1-(1-methyl-2-((alpha-phenyl-o-tolyl)oxy)ethyl)-, phosphate Piperidine, 1-(1-methyl-2-(2-(phenylmethyl)phenoxy)ethyl)-, phosphate (9CI)
CAS	19428-14-9;3563-76-6
EINECS	243-050-0
Chemical Formula	C21H30NO5P
Molecular Weight	407.44
inchi	InChI=1/C21H27NO.H3O4P/c1-18(22-14-8-3-9-15-22)17-23-21-13-7-6-12-20(21)16-19-10-4-2-5-11-19;1-5(2,3)4/h2,4-7,10-13,18H,3,8-9,14-17H2,1H3;(H3,1,2,3,4)
Package	10 mM * 1 mL;100 mg
Price	Email to quote
Descriptions	Benproperine phosphate Benproperine phosphate MedChemExpress (MCE) HY-114657A 19428-14-9 99.93% 4°C, sealed storage, away from moisture In solvent : -80°C, 2 years Descriptions Benproperine phosphate Benproperine phosphate MedChemExpress (MCE) HY-114657A 19428-14-9 99.93% 4°C, sealed storage, away from moisture In solvent : -80°C, 2 years -20°C, 1 year (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Benproperine phosphate is an orally active, potent actin-related protein 2/3 complex subunit 2 (ARPC2) inhibitor. Benproperine phosphate attenuates the actin polymerization rate of action polymerization nucleation by impairing Arp2/3 function. Benproperine phosphate has the potential for a cough suppressant and suppresses cancer cell migration and tumor metastasis. Benproperine phosphate (20-120 μM for 24 hours) inhibits cell viability in a dose-dependent manner[1]. Benproperine phosphate (10 μM for 24 hours) significantly inhibits the migration of various types of cancer cells and inhibits the migration and invasion of DLD-1, AsPC-1 cells with IC50 values of 1-2 μM. Benproperine phosphate (10 μM for 24 hours) does not affect cortactin-rich lamellipodium in MCF-10A cells[1]. Benproperine phosphate (50, 100 mg/kg oral gavage 5 days per week for 4 weeks) inhibits primary pancreatic tumor growth[1]. Benproperine phosphate shows a marked decrease in the lung metastasis of AsPC-1 cells (56.1% inhibition) in mouse. Benproperine phosphate significantly suppressed the liver metastasis of HCT-116 cells by 78.9% and DLD-1 cells by 78.2%[1]. \| \| \| \| \| \| \| \| \| \| [1]. Yae Jin Yoon, et al. Benproperine, an ARPC2 inhibitor, suppresses cancer cell migration and tumor metastasis. Biochem Pharmacol. 2019 May 163:46-59. [Content Brief]
Last Update	2025-04-01 14:45:47

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