(2S,4S)-Sacubitril MedChemExpress (MCE)

Product Name	LCZ 696 Impurity C
Synonyms	(2S,4S)-Sacubitril LCZ 696 Impurity C Sacubitril Impurity C 4-(((2S,4S)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid 1,1'-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-, α-ethyl ester, (αS,γS)- Synonyms (2S,4S)-Sacubitril LCZ 696 Impurity C Sacubitril Impurity C 4-(((2S,4S)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid 1,1'-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-, α-ethyl ester, (αS,γS)- [1,1'-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-, α-ethyl ester, (αS,γS)- [1,1'-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-, ethyl ester, [S-(R,R)]- (9CI)
CAS	149709-63-7
EINECS
Chemical Formula	C24H29NO5
Molecular Weight	411.49
inchi
Package	10 mM * 1 mL;1 mg
Price	Email to quote
Descriptions	(2S,4S)-Sacubitril (2S,4S)-Sacubitril MedChemExpress (MCE) HY-78841 149709-63-7 Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions (2S,4S)-Sacubitril (2S,4S)-Sacubitril MedChemExpress (MCE) HY-78841 149709-63-7 Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. (2S,4S)-Sacubitril is the impurity of Sacubitril. Sacubitril is a potent NEP inhibitor that can be used for the research of heart failure. (2S,4S)-Sacubitril is a stereoisomer derived from Sacubitril[1]. \| \| \| \| \| \| \| \| \| \| [1]. Halama A, et, al. Synthesis, Isolation, and Analysis of Stereoisomers of Sacubitril. Org. Process Res. Dev. 2019, 23, 1, 102-107. [2]. Shi J, et al. Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation. Drug Metab Dispos. 2016 Apr 44(4):554-9. [Content Brief]
Supplier Website	https://www.medchemexpress.com/2S,4S-Sacubitril.html
Last Update	2025-05-21 16:50:25

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