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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product NameEserine Salicylate
Synonymsar-44
Eserine Salicylate
ESERINE SALICYLATE
ESERINE MONOSALICYLATE
ESERINE SALICYLATE SALT
PHYSOSTIGMINE SALICYLATE
PHYSOSTIGMINE SALICYLATE SALT

Synonyms

ar-44
Eserine Salicylate
ESERINE SALICYLATE
ESERINE MONOSALICYLATE
ESERINE SALICYLATE SALT
PHYSOSTIGMINE SALICYLATE
PHYSOSTIGMINE SALICYLATE SALT
2-hydroxy-,compd.with(3as-cis)-1,2,3,3a,8,8a-hexahydro-1,3a,8-benzoicaci
CAS57-64-7
EINECS200-343-8
Chemical FormulaC22H27N3O5
Molecular Weight413.47
inchi
Package10 mM * 1 mL;1 mg;5 mg;10 mg;25 mg;50 mg
PriceEmail to quote
DescriptionsPhysostigmine salicylate

Physostigmine salicylate

MedChemExpress (MCE)

HY-B1266

57-64-7

Eserine salicylate

98.80%

4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months

Descriptions

Physostigmine salicylate

Physostigmine salicylate

MedChemExpress (MCE)

HY-B1266

57-64-7

Eserine salicylate

98.80%

4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months
-20°C, 1 month (sealed storage, away from moisture and light)

Room temperature in continental US
may vary elsewhere.

Physostigmine salicylate (Eserine salicylate) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine salicylate crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine salicylate can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine salicylate is also an antidote for anticholinergic poisoning.

Physostigmine salicylate (Eserine salicylate
0.03-0.3 mg/kg
s.c.
daily for 6 weeks) improves deficits in contextual and cued memory in Tg(+) mice[2].?

AChE

| | | |

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[1]. Haase U, et al. Pharmakotherapie--physostigmin post OP [Pharmacotherapy--physostigmine administered post-operatively]. Anasthesiol Intensivmed Notfallmed Schmerzther. 2007
42(3):188‐189.
[Content Brief]

[2]. Dong H, et al, Bertchume A, Vallera D, Csernansky JG. Acetylcholinesterase inhibitors ameliorate behavioral deficits in the Tg2576 mouse model of Alzheimer's disease. Psychopharmacology (Berl). 2005
181(1):145‐152.
[Content Brief]

[3]. Frascogna N. Physostigmine: is there a role for this antidote in pediatric poisonings?. Curr Opin Pediatr. 2007
19(2):201‐205.
[Content Brief]

[4]. Jonathan D Kenny, et al. Physostigmine and Methylphenidate Induce Distinct Arousal States During Isoflurane General Anesthesia in Rats. Anesth Analg. 2016 Nov
123(5):1210-1219.
[Content Brief]

Supplier Websitehttps://www.medchemexpress.com/physostigmine-salicylate.html
Last Update2025-05-21 16:50:25
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