Aldadiene potassium; SC-14266 MedChemExpress (MCE)

Product Name	canrenoic acid potassium
Synonyms	Canrenoate POTASSIUM CANRENOATE Potassium canrenoate Canrenoate Potassium canrenoic acid potassium Canrenone, potassium salt CANRENOIC ACID POTASSIUM SALT Synonyms Canrenoate POTASSIUM CANRENOATE Potassium canrenoate Canrenoate Potassium canrenoic acid potassium Canrenone, potassium salt CANRENOIC ACID POTASSIUM SALT 17-HYDROXY-3-OXOPREGNA-4,6-DIENE-21-CARBOXYLIC ACID 17-HYDROXY-3-OXOPREGNA-4,6-DIENE-21-CARBOXYLIC ACID POTASSIUM SALT 4,6-ANDROSTADIEN-17ALPHA-YL-PROPIONIC ACID-17BETA-OL-3-ONE POTASSIUM SALT potassium 3-[(10R,13S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoate (non-preferred name) potassium 3-[(8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoate (non-preferred name)
CAS	2181-04-6
EINECS	218-554-9
Chemical Formula	C11H15KO2
Molecular Weight	218.33
inchi	InChI=1/C22H30O4.K/c1-20-9-5-15(23)13-14(20)3-4-16-17(20)6-10-21(2)18(16)7-11-22(21,26)12-8-19(24)25;/h3-4,13,16-18,26H,5-12H2,1-2H3,(H,24,25);/q;+1/p-1/t16?,17?,18?,20-,21-,22+;/m0./s1
Package	10 mM * 1 mL;100 mg;500 mg
Price	Email to quote
Descriptions	Canrenoate potassium Canrenoate potassium MedChemExpress (MCE) HY-B1582A 2181-04-6 Aldadiene potassium Descriptions Canrenoate potassium Canrenoate potassium MedChemExpress (MCE) HY-B1582A 2181-04-6 Aldadiene potassium SC-14266 99.89% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Canrenoate (Aldadiene) potassium, a proagent that releases canrenone, is a potent, competitive mineralocorticoid receptor (aldosterone receptor) antagonist. Potassium canrenoate, as a diuretic, is used for the research of hypertension. Potassium canrenoate has been shown to cause in rats a dose-dependent increase in myelogenous leukemia and statistically significant increases in malignant tumor of the liver, thyroid, brain and mammary gland[2][3]. Potassium canrenoate (20 mg/kg/day drinking water) reduces isoprenaline-induced cardiac fibrosis in the rat[4]. \| \| \| \| \| \| \| \| \| \| [1]. Iqbal J, Andrew R, et al. Displacement of cortisol from human heart by acute administration of a mineralocorticoid receptor antagonist. J Clin Endocrinol Metab. 2014 99(3):915-922. [Content Brief]*
Last Update	2025-04-01 14:45:47

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