Diphenyl MedChemExpress (MCE)

Product Name	diphenyl hydrogen phosphate
Synonyms	NSC 6518 BRN 1379164 Biphenyl Ester Diphenyl phosphate DIPHENYL PHOSPHATE Phosphoric acid diphenyl Phenyl hydrogen phosphate Synonyms NSC 6518 BRN 1379164 Biphenyl Ester Diphenyl phosphate DIPHENYL PHOSPHATE Phosphoric acid diphenyl Phenyl hydrogen phosphate Diphenyl hydrogen phosphate diphenyl hydrogen phosphate PHOSPHORIC ACID DIPHENYL ESTER Phosphoric acid, diphenyl ester Phenyl phosphate ((PhO)2(HO)PO) PHOSPHORIC ACID DIPLHENYL ESTER Phosphoric acid hydrogen diphenyl ester 4-06-00-00714 (Beilstein Handbook Reference)
CAS	838-85-7
EINECS	212-657-2
Chemical Formula	C12H11O4P
Molecular Weight	250.19
inchi	InChI=1/C12H11O4P/c13-17(14,15-11-7-3-1-4-8-11)16-12-9-5-2-6-10-12/h1-10H,(H,13,14)/p-1
Package	10 mM * 1 mL;5 g
Price	Email to quote
Descriptions	Diphenyl Phosphate Diphenyl Phosphate MedChemExpress (MCE) HY-W008151 838-85-7 99.94% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions Diphenyl Phosphate Diphenyl Phosphate MedChemExpress (MCE) HY-W008151 838-85-7 99.94% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Diphenyl Phosphate inhibits growth and energy metabolism in zebrafish and mice in a sex-specific manner. Diphenyl Phosphate can inhibit the activity of SDH (respiratory complex II), reduce the expression of CPT1 and disrupts the integrity of the mitochondrial membrane. Diphenyl Phosphate may be used in research on metabolic diseases. Diphenyl Phosphate (2 or 200 mg/kg, s.c., once daily for 10 days) has no adverse effects on uterine weight and serum estradiol levels in ICR mice, but causes disturbances in lipid metabolism characteristics[2]. Chronic exposure to DPhP (0.8-35.6 μg/L, exposure for 120 days) can retard growth in male zebrafish by inhibiting energy output[1]. Succinate Dehydrogenase (SDH) Carnitine Palmitoyltransferase 1 (CPT1) In Vivo Diphenyl Phosphate (2 or 200 mg/kg, s.c., once daily for 10 days) has no adverse effects on uterine weight and serum estradiol levels in ICR mice, but causes disturbances in lipid metabolism characteristics[2]. Chronic exposure to DPhP (0.8-35.6 μg/L, exposure for 120 days) can retard growth in male zebrafish by inhibiting energy output[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Primigravida ICR mice (days 1-10 post-birth)[2] \| \| \| \| \| \| \| \| \| \| [1]. Chen Q, et al. Life Cycle Exposure to Environmentally Relevant Concentrations of Diphenyl Phosphate (DPhP) Inhibits Growth and Energy Metabolism of Zebrafish in a Sex-Specific Manner. Environ Sci Technol. 2021 Oct 5 55(19):13122-13131. [Content Brief] [2]. Wang D, et al. Neonatal triphenyl phosphate and its metabolite diphenyl phosphate exposure induce sex- and dose-dependent metabolic disruptions in adult mice. Environ Pollut. 2018 Jun 237:10-17. [Content Brief]
Last Update	2025-04-01 14:45:47

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