Boc-Hyp-OH MedChemExpress (MCE)

Product Name	boc-L-hydroxyproline
Synonyms	N-ter Boc-Hyp-OH boc-L-hydroxyproline N-T-bocl-hydroxyproline Boc-trans-4-hydroxy-L-proline (2S,4R)-1-Boc-4-Hydroxy-Proline N-BOC-trans-4-hydroxy-L-proline Synonyms N-ter Boc-Hyp-OH boc-L-hydroxyproline N-T-bocl-hydroxyproline Boc-trans-4-hydroxy-L-proline (2S,4R)-1-Boc-4-Hydroxy-Proline N-BOC-trans-4-hydroxy-L-proline 1-(tert-butoxycarbonyl)-4-hydroxyproline (4R)-1-(tert-butoxycarbonyl)-4-hydroxy-L-proline Boc-(2S,4R)-4-Hydroxy-2-pyrrolidinecarboxylic Acid Boc-L-Hyp-OHN-(tert-Butoxycarbonyl)-L-4-hydroxyproline 4-Hydroxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester (2S,4R)-N-t-Butoxycarbonyl-4-hydroxypyrrolidine-2-carboxylic Acid (2S,4R)-1-(tertbutoxycarbonyl)-4-hydroxypyrrolidine carboxylic acid (2S)-1-[(tert-butoxy)carbonyl]-4-hydroxypyrrolidine-2-carboxylic acid (2S,4R)-4-hydroxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester (2S,4R)-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid 1,2-Pyrrolidinedicarboxylicacid,4-hydroxy-,1-(1,1-diMethylethyl)ester,(2S,4R)-
CAS	13726-69-7;331442-12-7
EINECS	604-011-7
Chemical Formula	C10H17NO5
Molecular Weight	231.25
inchi	InChI=1/C10H17NO5/c1-10(2,3)16-9(15)11-5-6(12)4-7(11)8(13)14/h6-7,12H,4-5H2,1-3H3,(H,13,14)
Package	5 g;10 g;25 g;100 g
Price	Email to quote
Descriptions	Boc-Hyp-OH Boc-Hyp-OH MedChemExpress (MCE) HY-I0781 13726-69-7 99.78% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions Boc-Hyp-OH Boc-Hyp-OH MedChemExpress (MCE) HY-I0781 13726-69-7 99.78% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Boc-Hyp-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-Hyp-OH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2] ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].PROTACs contain two different ligands connected by a linker one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. Non-cleavable Linker \| \| \| \| \| \| \| \| \| \| [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 16(5):315-337. [Content Brief] [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020 27(8):998-985. [Content Brief]
Supplier Website	https://www.medchemexpress.com/boc-hyp-oh.html
Last Update	2025-05-21 16:50:25

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