Fmoc-azetidine-3-carboxylic acid MedChemExpress (MCE)

Product Name	Fmoc-Azetidine-3-carboxylic acid
Synonyms	FMOC-AZE(3)-OH Fmoc-AZE(3)-OH RARECHEM BK PT 0279 FMOC-AZETIDINE-3-CARBOXYLIC ACID Fmoc-Azetidine-3-carboxylic acid FMOC-3-AZETIDINE CARBOXYLIC ACID N-Fmoc-3-Azetidine carboxylic acid Synonyms FMOC-AZE(3)-OH Fmoc-AZE(3)-OH RARECHEM BK PT 0279 FMOC-AZETIDINE-3-CARBOXYLIC ACID Fmoc-Azetidine-3-carboxylic acid FMOC-3-AZETIDINE CARBOXYLIC ACID N-Fmoc-3-Azetidine carboxylic acid Fmoc-L-Azetidine-3-carboxylic acid N-FMOC-3-AZETIDINE CARBOXYLIC ACID 1-Fmoc-Azetidine-3-carboxylic acid N-ALPHA-FMOC-L-AZETIDINE-3-CARBOXYLIC ACID N-Alpha-Fmoc-L-Azetidine-3-carboxylic acid 1-[(9H-Fluoren-9-ylmethoxy)carbonyl]azetidine-3-carboxylic acid N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-AZETIDINE-3-CARBOXYLIC ACID N-Alpha-(9-fluorenylmethoxycarbonyl)-Azetidine-3-carboxylic acid N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-azetidine-3-carboxylic acid 1-(((9H-Fluoren-9-yl)methoxy)carbonyl) Azetidine-3-carboxylic acid N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-Azetidine-3-carboxylic acid
CAS	193693-64-0
EINECS
Chemical Formula	C19H17NO4
Molecular Weight	323.34
inchi	InChI=1/C19H17NO4/c21-18(22)12-9-20(10-12)19(23)24-11-17-15-7-3-1-5-13(15)14-6-2-4-8-16(14)17/h1-8,12,17H,9-11H2,(H,21,22)
Package	250 mg;1 g;5 g;10 g;25 g
Price	Email to quote
Descriptions	Fmoc-azetidine-3-carboxylic acid Fmoc-azetidine-3-carboxylic acid MedChemExpress (MCE) HY-W011277 193693-64-0 98.72% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions Fmoc-azetidine-3-carboxylic acid Fmoc-azetidine-3-carboxylic acid MedChemExpress (MCE) HY-W011277 193693-64-0 98.72% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Fmoc-azetidine-3-carboxylic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].PROTACs contain two different ligands connected by a linker one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. Non-cleavable Linker \| \| \| \| \| \| \| \| \| \| [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 16(5):315-337. [Content Brief] [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020 27(8):998-985. [Content Brief]
Last Update	2025-04-01 14:45:47

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