Tofisopam MedChemExpress (MCE)

Product Name	Tofisopam
Synonyms	Tosopam TOFISOPAM tofizopam Tofisopam TOFISOPAM 22345-47-7 1-(3,4-Dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine 1-(3,4-Dimethoxyphenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5H-2,3-benzodiazepine Synonyms Tosopam TOFISOPAM tofizopam Tofisopam TOFISOPAM 22345-47-7 1-(3,4-Dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine 1-(3,4-Dimethoxyphenyl)-4-methyl-5-ethyl-7,8-dimethoxy-5H-2,3-benzodiazepine 7,8-DIMETHOXY-1-(3,4-DIMETHOXYPHENYL)-5-ETHYL-4-METHYL-5H-2,3-BENZODIAZEPINE 1-(3,4-Dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5H-benzo[d][1,2]diazepine 5H-2,3-Benzodiazepine, 1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl- (8CI, 9CI)
CAS	22345-47-7
EINECS	244-922-3
Chemical Formula	C22H26N2O4
Molecular Weight	382.45
inchi	InChI=1/C22H26N2O4/c1-7-15-13(2)23-24-22(14-8-9-18(25-3)19(10-14)26-4)17-12-21(28-6)20(27-5)11-16(15)17/h8-12,15H,7H2,1-6H3
Package	10 mM * 1 mL;5 mg;10 mg;25 mg;50 mg;100 mg;200 mg
Price	Email to quote
Descriptions	Tofisopam Tofisopam MedChemExpress (MCE) HY-A0165 22345-47-7 99.46% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions Tofisopam Tofisopam MedChemExpress (MCE) HY-A0165 22345-47-7 99.46% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Tofisopam, a 2,3-benzodiazepine compound, is an orally active anxiolytic agent. Tofisopam can inhibit phosphodiesterase PDE isoenzyme activity. Tofisopam administration at a dose of 50 mg/kg for seven days improves the impaired cognitive performance, enhances the attenuated synaptic transmission in the hippocampus, increases proliferation in subgranular zones, and improves the decrease in astrocytes in amnesic rats[1]. \| \| \| \| \| \| \| \| \| \| [1]. Rundfeldt C, et al. The atypical anxiolytic drug, tofisopam, selectively blocks phosphodiesterase isoenzymes and is active in the mouse model of negative symptoms of psychosis[J]. Journal of neural transmission, 2010, 117: 1319-1325. [2]. Umut İrfan Üçel, et al. Antiamnesic effects of tofisopam against scopolamine-induced cognitive impairments in rats. Pharmacol Biochem Behav. 2020 Mar 190:172858. [Content Brief]
Last Update	2025-04-01 14:45:47

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