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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product NameZJ 43
SynonymsZJ 43
CAS723331-20-2
EINECS
Chemical FormulaC12H20N2O7
Molecular Weight304.3
inchi
Package1 mg
PriceEmail to quote
DescriptionsZJ43

ZJ43

MedChemExpress (MCE)

HY-103344

723331-20-2

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US

Descriptions

ZJ43

ZJ43

MedChemExpress (MCE)

HY-103344

723331-20-2

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US
may vary elsewhere.

ZJ43 is a potent NAAG peptidase inhibitor, with an IC50 of 2.4 nM and a Ki of 0.8 nM. ZJ43 sufficiently activates group II mGluR and reduces some of the behavioral effects of PCP. ZJ43 shows an analgesic effect in neuropathic and inflammatory and pain models.

IC50: 2.4 nM (NAAG)[1] Molecular Weight 304.30

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[1]. Olszewski RT, et al. NAAG peptidase inhibition reduces locomotor activity and some stereotypes in the PCP model of schizophrenia via group II mGluR. J Neurochem. 2004 May
89(4):876-85. [Content Brief]

[2]. Yamamoto T, et al. Antinociceptive effects of N-acetylaspartylglutamate (NAAG) peptidase inhibitors ZJ-11, ZJ-17 and ZJ-43 in the rat formalin test and in the rat neuropathic pain model. Eur J Neurosci. 2004 Jul
20(2):483-94. [Content Brief]

Supplier Websitehttps://www.medchemexpress.com/zj43.html
Last Update2025-05-21 16:50:25
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