RKI-1313 MedChemExpress (MCE)

Product Name	1-(3-Methoxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea
Synonyms	RKI1313 PKI1313 RKI-1313 RKI 1313 PKI 1313 RKI-1313 (Negative control of RKI-1447) 1-(3-METHOXYBENZYL)-3-(4-(PYRIDIN-4-YL)THIAZOL-2-YL)UREA Synonyms RKI1313 PKI1313 RKI-1313 RKI 1313 PKI 1313 RKI-1313 (Negative control of RKI-1447) 1-(3-METHOXYBENZYL)-3-(4-(PYRIDIN-4-YL)THIAZOL-2-YL)UREA 1-(3-Methoxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea Urea, N-[(3-methoxyphenyl)methyl]-N'-[4-(4-pyridinyl)-2-thiazolyl]-
CAS	1342276-76-9
EINECS
Chemical Formula	C17H16N4O2S
Molecular Weight	340.4
inchi
Package	1 mg;5 mg
Price	Email to quote
Descriptions	RKI-1313 RKI-1313 MedChemExpress (MCE) HY-107209 1342276-76-9 98.2% Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions RKI-1313 RKI-1313 MedChemExpress (MCE) HY-107209 1342276-76-9 98.2% Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. RKI-1313 is a ROCK inhibitor with IC50s of 34, 8 µM for ROCK 1 and ROCK 2, respectively. RKI-1313 shows little effect on the phosphorylation levels of ROCK substrates, migration, invasion or anchorage-independent growth. ROCK1 34 μM (IC50) ROCK2 8 μM (IC50) \| \| \| \| \| \| \| \| \| \| [1]. Patel RA, et al. RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer. Cancer Res. 2012 Oct 1 72(19):5025-34. [Content Brief]
Last Update	2025-04-01 14:45:47

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