Dicorantil phosphate; SC-7031 phosphate MedChemExpress (MCE)

Product Name	disopyramide phosphate
Synonyms	Norpace SC 13957 RYTHMODAN Rythmodan norpace cr Norpace CR UNII-N6BOM1935W Synonyms Norpace SC 13957 RYTHMODAN Rythmodan norpace cr Norpace CR UNII-N6BOM1935W SC 7031 phosphate disopyramid phosphate DISOPYRAMIDE PHOSPHATE Disopyramide phosphate disopyramide phosphate DISOPYRAMIDE PHOSPHATE SALT 4-(dipropan-2-ylamino)-2-phenyl-2-(pyridin-2-yl)butanamide 4-(diisopropylaMino)-2-phenyl-2-(pyridin-2-yl)butanaMide phosphate alpha-(2-Diisopropylaminoethyl)-alpha-phenyl-2-pyridineacetamide phosphate ALPHA-DIISOPROPYLAMINOETHYL-ALPHA-PHENYLPYRIDINE-2-ACET-AMIDE PHOSPHATE SALT 2-Pyridineacetamide, alpha-(2-(diisopropylamino)ethyl)-alpha-phenyl-, phosphate 2-(1-(Ammoniocarbonyl)-3-(diisopropylammonio)-1-phenylpropyl)pyridinium phosphate 2-[1-(ammoniocarbonyl)-3-(diisopropylammonio)-1-phenylpropyl)]pyridinium phosphate 2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-, phosphate (9CI)
CAS	22059-60-5
EINECS	244-756-1
Chemical Formula	C21H32N3O5P
Molecular Weight	437.47
inchi	InChI=1/C21H29N3O.H3O4P/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19;1-5(2,3)4/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25);(H3,1,2,3,4)
Package	5 mg;10 mg;50 mg;100 mg
Price	Email to quote
Descriptions	Disopyramide phosphate Disopyramide phosphate MedChemExpress (MCE) HY-12533A 22059-60-5 Dicorantil phosphate Descriptions Disopyramide phosphate Disopyramide phosphate MedChemExpress (MCE) HY-12533A 22059-60-5 Dicorantil phosphate SC-7031 phosphate 99.85% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Disopyramide phosphate is a class IA antiarrhythmic agent with efficacy in ventricular and atrial arrhythmias. Disopyramide phosphate blocks the fast inward sodium current of cardiac muscle and prolongs the duration of cardiac action potentials. Disopyramide phosphate inhibits HERG encoded potassium channels. Disopyramide phosphate also exhibits complex protein binding, and has a potent negative inotropic action. HERG tail currents recorded at -40 mV following test pulses to +30 mV were inhibited in a dose-dependent fashion by Disopyramide concentrations within the clinical range (IC50=7.23 μM)[1]. \| \| \| \| \| \| \| \| \| \| [1]. S V Jones, et al. Non-competitive Effects of Disopyramide at the Neuromuscular Junction: Evidence for Endplate Ion Channel Block. Br J Anaesth. 1987 Jun 59(6):776-83. [Content Brief]* [2]. L A Siddoway, et al. Clinical Pharmacokinetics of Disopyramide. Clin Pharmacokinet. May-Jun 1986 11(3):214-22. [Content Brief] [3]. A A Paul, et al. Inhibition of HERG Potassium Channel Current by the Class 1a Antiarrhythmic Agent Disopyramide. Biochem Biophys Res Commun. 2001 Feb 9 280(5):1243-50. [Content Brief]
Last Update	2025-04-01 14:45:47

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