Buflomedil MedChemExpress (MCE)

Product Name	Buflomedil
Synonyms	Buflomedil BUFLOMEDIL AURORA KA-850 BufluomedilHcl 2',4',6'-Trimethoxy-4-(1-pyrrolidinyl)butyrophenone 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanon 1-Butanone, 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-
CAS	55837-25-7
EINECS	259-851-3
Chemical Formula	C17H25NO4
Molecular Weight	307.38
inchi
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Descriptions	Buflomedil Buflomedil MedChemExpress (MCE) HY-B0484A 55837-25-7 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Buflomedil Buflomedil MedChemExpress (MCE) HY-B0484A 55837-25-7 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Buflomedil, a vasodilator agent, is an orally active α1A-adrenoceptor antagonist with Kis of 4.06 µM and 6.84 µM for α1A-AR and α1B-AR, respectively. Buflomedil can be used for the study of peripheral circulatory disorders. rat α1A-adrenergic receptor 4.06 μM (Ki) α1B-adrenergic receptor 6.84 μM (Ki) \| \| \| \| \| \| \| \| \| \| [1]. de Backer TL, et al. Buflomedil for intermittent claudication. Cochrane Database Syst Rev. 2013 Mar 28 2013(3):CD000988. [Content Brief] [2]. Limbs International Medicinal Buflomedil (LIMB) Study Group Leizorovicz A, Becker F. Oral buflomedil in the prevention of cardiovascular events in patients with peripheral arterial obstructive disease: a randomized, placebo-controlled, 4-year study. Circulation. 2008 Feb 12 117(6):816-22. [Content Brief] [3]. Tang LM, et al. Inhibitory effect of buflomedil on prostate alpha1A adrenoceptor in the Wistar rat. Neurosci Lett. 2004 Sep 2 367(2):224-7. [Content Brief]
Last Update	2025-04-01 14:45:47

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