Lys01 MedChemExpress (MCE)

Product Name	N2-(7-Chloro-4-quinolinyl)-N1-[2-[(7-chloro-4-quinolinyl)amino]ethyl]-N1-methyl-1,2-ethanediamine
Synonyms	LYS05 LYS-05 LYS 05 CS-2372 LYS01 free base N2-(7-Chloro-4-quinolinyl)-N1-[2-[(7-chloro-4-quinolinyl)amino]ethyl]-N1-methyl-1,2-ethanediamine N1-(7-chloroquinolin-4-yl)-N2-(2-((7-chloroquinolin-4-yl)amino)ethyl)-N2-methylethane-1,2-diamine Synonyms LYS05 LYS-05 LYS 05 CS-2372 LYS01 free base N2-(7-Chloro-4-quinolinyl)-N1-[2-[(7-chloro-4-quinolinyl)amino]ethyl]-N1-methyl-1,2-ethanediamine N1-(7-chloroquinolin-4-yl)-N2-(2-((7-chloroquinolin-4-yl)amino)ethyl)-N2-methylethane-1,2-diamine N2-(7-Chloro-4-quinolinyl)-N1-[2-[(7-chloro-4-quinolinyl)aMino]ethyl]-N1-Methyl-1,2-ethanediaMine
CAS	1391426-22-4
EINECS
Chemical Formula	C23H23Cl2N5
Molecular Weight	440.37
inchi
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Descriptions	Lys01 Lys01 MedChemExpress (MCE) HY-12855 1391426-22-4 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Lys01 Lys01 MedChemExpress (MCE) HY-12855 1391426-22-4 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Lys01, a dimeric form of Chloroquine (HY-17589A), is an autophagy inhibitor. Lys01 inhibits cell viability of 1205Lu, c8161, LN229, HT-29 cells with IC50s of 3.6, 3.8, 7.9, 6.0 μM. Lys01 can be used for anticancer research. \| \| \| \| \| \| \| \| \| \| [1]. McAfee Q, et al. Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency. Proc Natl Acad Sci U S A. 2012 May 22 109(21):8253-8. [Content Brief]
Last Update	2025-04-01 14:45:47

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