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Supplier NameMedChemExpress (MCE)
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Product NameCyclobenzaprine N-Oxide
SynonymsCyclobenzalin N-oxide
Cyclobenzaprine N-Oxide
N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-delta 5,alpha-propylamine N-oxide
3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine N-Oxide

Synonyms

Cyclobenzalin N-oxide
Cyclobenzaprine N-Oxide
N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-delta 5,alpha-propylamine N-oxide
3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine N-Oxide
1-Propanamine, 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-, N-oxide
CAS6682-26-4
EINECS
Chemical FormulaC20H21NO
Molecular Weight291.39
inchi
Package1 mg;5 mg;10 mg
PriceGet quote
DescriptionsCyclobenzaprine N-oxide

Cyclobenzaprine N-oxide

MedChemExpress (MCE)

HY-133797

6682-26-4

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US

Descriptions

Cyclobenzaprine N-oxide

Cyclobenzaprine N-oxide

MedChemExpress (MCE)

HY-133797

6682-26-4

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US
may vary elsewhere.

Cyclobenzaprine N-oxide is the tertiary amine metabolite of Cyclobenzaprine (HY-B0740) in liver particles. Cyclobenzaprine is a skeletal muscle relaxant and is active on the central nervous system. The liver cytosol from liver particles has reductase activity that can reduce Cyclobenzaprine N-oxide to the corresponding amine.

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[1]. Kitamura S, et al. Reduction of tertiary amine N-oxides by liver preparations: function of aldehyde oxidase as a major N-oxide reductase. Biochem Biophys Res Commun. 1984 Jun 29
121(3):749-54.
[Content Brief]

[2]. Kobayashi, et al. Ono, Cyclobenzaprine, a centrally acting muscle relaxant, acts on descending serotonergic systems. Eur J Pharmacol, 1996. 311(1): p. 29-35. [Content Brief]

[3]. Belvedere G, et al. Identification of cyclobenzaprine-10, 11-epoxide and other metabolites after incubation of cyclobenzaprine with rat liver microsomes[J]. Xenobiotica, 1975, 5(12): 765-771.

Supplier Websitehttps://www.medchemexpress.com/cyclobenzaprine-n-oxide.html
Last Update2025-05-21 16:50:25
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