Ro 14-4767; Ro 14-4767/000 MedChemExpress (MCE)

Product Name	Amorolfine
Synonyms	Fradafi SYLIMARIN AMOROLFINE Fradafiban Amorolfine (2R,6S)-4-[3-(4-tert-amylphenyl)-2-methyl-propyl]-2,6-dimethyl-morpholine cis-4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethylmorpholine Synonyms Fradafi SYLIMARIN AMOROLFINE Fradafiban Amorolfine (2R,6S)-4-[3-(4-tert-amylphenyl)-2-methyl-propyl]-2,6-dimethyl-morpholine cis-4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethylmorpholine (2R,6S)-2,6-dimethyl-4-[2-methyl-3-[4-(2-methylbutan-2-yl)phenyl]propyl]morpholine
CAS	67467-83-8;78613-35-1
EINECS	1312995-182-4
Chemical Formula	C21H35NO
Molecular Weight	317.51
inchi	InChI=1/C21H35NO/c1-7-21(5,6)20-10-8-19(9-11-20)12-16(2)13-22-14-17(3)23-18(4)15-22/h8-11,16-18H,7,12-15H2,1-6H3/t16?,17-,18+
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Descriptions	Amorolfine Amorolfine MedChemExpress (MCE) HY-121169 78613-35-1 Ro 14-4767 Descriptions Amorolfine Amorolfine MedChemExpress (MCE) HY-121169 78613-35-1 Ro 14-4767 Ro 14-4767/000 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Amorolfine (Ro 14-4767) is an antifungal agent. Amorolfine ameliorates the onychomycosis through inhibition of ergosterol biosynthesis. Amorolfine inhibits Candida albicans with a MIC of 0.404 µg/mL. \| \| \| \| \| \| \| \| \| \| [1]. Pittrof F, et al., Loceryl nail lacquer--realization of a new galenical approach to onychomycosis therapy. Clin Exp Dermatol. 1992 Sep 17 Suppl 1:26-8. [Content Brief] [2]. Haria M, et al. Amorolfine. A review of its pharmacological properties and therapeutic potential in the treatment of onychomycosis and other superficial fungal infections. Drugs. 1995 Jan 49(1):103-20. [Content Brief]
Supplier Website	https://www.medchemexpress.com/amorolfine.html
Last Update	2025-05-21 16:50:25

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