Acefylline MedChemExpress (MCE)

Product Name	1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purine-7-acetic acid, compound with piperazine (2:1)
Synonyms	dynaphylline aethaphyllinium acefyllinpiperazinate Acephylline piperazine acefyllinepiperazinesalt piperazinetheophyllineethanoate theophyllineethanoateofpiperazine Synonyms dynaphylline aethaphyllinium acefyllinpiperazinate Acephylline piperazine acefyllinepiperazinesalt piperazinetheophyllineethanoate theophyllineethanoateofpiperazine 1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7h-purine-7-aceticacicompd.wit 1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7h-purine-7-aceticacidcompd.with
CAS	18833-13-1
EINECS	242-614-3
Chemical Formula	C13H20N6O4
Molecular Weight	324.34
inchi	InChI=1/2C9H10N4O4.C4H10N2/c21-11-7-6(8(16)12(2)9(11)17)13(4-10-7)3-5(14)15;1-2-6-4-3-5-1/h24H,3H2,1-2H3,(H,14,15);5-6H,1-4H2
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Descriptions	Acefylline piperazine Acefylline piperazine MedChemExpress (MCE) HY-B1505A 18833-13-1 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Acefylline piperazine Acefylline piperazine MedChemExpress (MCE) HY-B1505A 18833-13-1 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Acefylline piperazine, a xanthine derivative, is an Adenosine Receptor antagonist. Acefylline piperazine is a peptidylarginine deiminase (PAD) activator. Acefylline piperazine is also a bronchodilator and cardiac stimulant that inhibits rat lung cAMP phosphodiesterase isoenzymes. Acefylline piperazine can be used in asthma research. Acefylline piperazine (200 μM 5-180 min) is an effective PDA activator[2]. \| \| \| \| \| \| \| \| \| \| [1]. Ferretti C, et al. Inhibitory effect of theophylline, theophylline-7-acetic acid, ambroxol and ambroxol-theophylline-7-acetate on rat lung cAMP phosphodiesterase isoenzymes. Int J Tissue React. 1992 14(1):31-6. [Content Brief] [2]. Méchin MC, et, al. Acefylline activates filaggrin deimination by peptidylarginine deiminases in the upper epidermis. J Dermatol Sci. 2016 Feb 81(2):101-6. [Content Brief] [3]. Tsvetkova B, Tencheva J, Peikov P. Esterification of 7-theophyllineacetic acid with diethylene glycol monomethyl ether. Acta Pharm. 2006 Jun 56(2):251-7. PMID: 16613730. [Content Brief]
Last Update	2025-04-01 14:45:47

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