YM060 free base MedChemExpress (MCE)

Product Name	RAMOSETRON
Synonyms	Nasea Nor-YM 060 RAMOSETRON (-)-(R)-1-Methylindol-3-yl 4,5,6,7-tetrahydro-5-benzimidazolylketone (1-Methyl-1H-indol-3-yl)[[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol]-5α-yl] ketone Methanone, (1-methyl-1H-indol-3-yl)(4,5,6,7-tetrahydro-1H-benzimidazol-5-yl)-, (R)- Synonyms Nasea Nor-YM 060 RAMOSETRON (-)-(R)-1-Methylindol-3-yl 4,5,6,7-tetrahydro-5-benzimidazolylketone (1-Methyl-1H-indol-3-yl)[[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol]-5α-yl] ketone Methanone, (1-methyl-1H-indol-3-yl)(4,5,6,7-tetrahydro-1H-benzimidazol-5-yl)-, (R)- Methanone, (1-methyl-1H-indol-3-yl)[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol-5-yl]- (9CI)
CAS	132036-88-5
EINECS
Chemical Formula	C17H17N3O
Molecular Weight	279.34
inchi
Package	Inquiry
Price	Get quote
Descriptions	Ramosetron Ramosetron MedChemExpress (MCE) HY-A0274 132036-88-5 YM060 free base Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Ramosetron Ramosetron MedChemExpress (MCE) HY-A0274 132036-88-5 YM060 free base Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Ramosetron (YM060 free base) is an orally active 5-HT3 antagonist that improves dysphoria, interference with activity and food avoidance. Ramosetron is promising for research of irritable bowel syndrome with diarrhea. Ramosetron (1 μM) inhibits 5-HT3 receptor-dependent 5-HT release in guinea pig colonic mucosa[3]. Ramosetron (0.01-0.1 mg/kg, p.o., twice daily for 5 days) Ameliorates 5-fluorouracil (5-FU) (HY-90006)-induced intestinal mucositis in C57BL/6 mice[2]. 5-HT3 Receptor \| \| \| \| \| \| \| \| \| \| [1]. http://www.drugsupdate.com/generic/view/1111 [2]. Yasuda M, et al. 5-HT₃ receptor antagonists ameliorate 5-fluorouracil-induced intestinal mucositis by suppression of apoptosis in murine intestinal crypt cells. Br J Pharmacol. 2013 Mar 168(6):1388-400. [Content Brief] [3]. Kojima SI, et al. Investigation of 5-HT3 receptor-triggered serotonin release from guinea-pig isolated colonic mucosa: a role of PYY-containing endocrine cell. Eur J Pharmacol. 2017 Mar 15 799:196-200. [Content Brief] [4]. Fukudo S, et al. Ramosetron Reduces Symptoms of Irritable Bowel Syndrome With Diarrhea and Improves Quality of Life in Women. Gastroenterology. 2016 Feb 150(2):358-66.e8. [Content Brief]
Supplier Website	https://www.medchemexpress.com/ramosetron.html
Last Update	2025-05-21 16:50:25

MedChemExpress (MCE) also provides

Thalidomide-4-O-C2-NH2

Category: Signaling Pathways
CAS: 2341840-99-9
Last Update: 2025-05-21 16:50:25

PPARα-MO-1

Category: Signaling Pathways
CAS: 810677-36-2
Last Update: 2025-05-21 16:50:25

Netupitant N-oxide

Category: Signaling Pathways
CAS: 910808-11-6
Last Update: 2025-05-21 16:50:25

MK-0812

Category: Signaling Pathways
CAS: 624733-88-6
Last Update: 2025-05-21 16:50:25

TS-011

Category: Signaling Pathways
CAS: 339071-18-0
Last Update: 2025-05-21 16:50:25

SCH 530348 sulfate

Category: Signaling Pathways
CAS: 705260-08-8
Last Update: 2025-05-21 16:50:25

BAG 956

Category: Signaling Pathways
CAS: 853910-02-8
Last Update: 2025-05-21 16:50:25

YM758

Category: Signaling Pathways
CAS: 312752-85-5
Last Update: 2025-05-21 16:50:25


Supplier Name	MedChemExpress (MCE)
Contact	sales
Tel	609-228-6898
Mobile	609-228-6898
QQ
Email	sales@medchemexpress.com; tech@medchemexpress.com
Website	https://www.medchemexpress.com/
Wechat

Request for quotation

Supplier Contact