AG 337 free base MedChemExpress (MCE)

Product Name	Nolatrexed
Synonyms	NOLA-012 Nolatrexed NOLATREXED Nolatrexed [inn] Nolatrexed fandachem 2-Amino-6-methyl-5-(4-pyridylthio)-4(3H)-quinazolinone 4(1H)-Quinazolinone, 2-amino-6-methyl-5-(4-pyridinylthio)- Synonyms NOLA-012 Nolatrexed NOLATREXED Nolatrexed [inn] Nolatrexed fandachem 2-Amino-6-methyl-5-(4-pyridylthio)-4(3H)-quinazolinone 4(1H)-Quinazolinone, 2-amino-6-methyl-5-(4-pyridinylthio)- 2-amino-6-methyl-5-(pyridin-4-ylsulfanyl)quinazolin-4(1H)-one 2-amino-6-methyl-5-(pyridin-4-ylsulfanyl)quinazolin-4(1H)-one dihydrochloride
CAS	147149-76-6
EINECS	1533716-785-6
Chemical Formula	C14H12N4OS
Molecular Weight	284.34
inchi	InChI=1/C14H12N4OS/c1-8-2-3-10-11(13(19)18-14(15)17-10)12(8)20-9-4-6-16-7-5-9/h2-7H,1H3,(H3,15,17,18,19)
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Descriptions	Nolatrexed Nolatrexed MedChemExpress (MCE) HY-13714 147149-76-6 AG 337 free base Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Nolatrexed Nolatrexed MedChemExpress (MCE) HY-13714 147149-76-6 AG 337 free base Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Nolatrexed (AG 337 free base) is a compound with antifolate activity, high oral bioavailability, and major toxicity at inhibitory doses is gastrointestinal reactions. It can be safely taken orally at specific doses for inhibition, with effects on platelets and neutrophils. \| \| \| \| \| \| \| \| \| \| [1]. Phase I studies with the nonclassical antifolate nolatrexed dihydrochloride (AG337, THYMITAQ) administered orally for 5 days [Content Brief]
Last Update	2025-04-01 14:45:47

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