(±)-Befunolol MedChemExpress (MCE)

Product Name	Befunolol
Synonyms	Befunolol 2-acetyl-7-(2-hyroxy-3-isopropylaminopropoxy)benzofuran 7-(2-hydroxy-3-(isopropylamino)propoxy)-2-benzofuranyl methyl ketone 1-(7-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-2-benzofuranyl)-ethanon Synonyms Befunolol 2-acetyl-7-(2-hyroxy-3-isopropylaminopropoxy)benzofuran 7-(2-hydroxy-3-(isopropylamino)propoxy)-2-benzofuranyl methyl ketone 1-(7-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-2-benzofuranyl)-ethanon Ethanone, 1-[7-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-2-benzofuranyl]-
CAS	39552-01-7
EINECS
Chemical Formula	C16H21NO4
Molecular Weight	291.34
inchi
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Descriptions	(±)-Befunolol (±)-Befunolol MedChemExpress (MCE) HY-101752 39552-01-7 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions (±)-Befunolol (±)-Befunolol MedChemExpress (MCE) HY-101752 39552-01-7 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. (±)-Befunolol is a β-adrenoceptor blocking agent. A β-adrenoceptor blocking agent, Befunolol, is found to has intrinsic sympathomimetic activities in isolated right atria, trachea and taenia caecum of guinea pig (intrinsic activities are 0.22-0.28). The pD2-values of Befunolol estimated in the isolated organs are significantly different from its pA2-values against isoprenaline. Befunolol interacts with the beta-adrenoceptor where there may be two different sites: one site for agonistic action and the other for competitive antagonistic action. The intrinsic activity of Befunolol may be equal to its selectivity for both the sites[1]. Adrenoreceptor[1] In Vitro A β-adrenoceptor blocking agent, Befunolol, is found to has intrinsic sympathomimetic activities in isolated right atria, trachea and taenia caecum of guinea pig (intrinsic activities are 0.22-0.28). The pD2-values of Befunolol estimated in the isolated organs are significantly different from its pA2-values against isoprenaline. Befunolol interacts with the beta-adrenoceptor where there may be two different sites: one site for agonistic action and the other for competitive antagonistic action. The intrinsic activity of Befunolol may be equal to its selectivity for both the sites[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> (±)-Befunolol Related Antibodies \| \| \| \| \| \| \| \| \| \| [1]. Takayanagi I, et al. A beta-adrenoceptor blocking agent, befunolol as a partial agonist in isolated organs. Gen Pharmacol. 1985 16(3):265-7. [Content Brief]
Last Update	2025-04-01 14:45:47

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