Palonosetron MedChemExpress (MCE)

Product Name	Palonosetron
Synonyms	2-Qhbiqo RS-25233-197 RS-25233-198 RS 25259-198 RS 25259-197 RS-25259-198 Palonosetron Synonyms 2-Qhbiqo RS-25233-197 RS-25233-198 RS 25259-198 RS 25259-197 RS-25259-198 Palonosetron RS 25233-197 Rs 25233-197 Palonosetron [inn] Palonosetron [INN] (S)-2-((S)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one 2-(1-Azabicyclo(2.2.2)oct-3-yl)-2,3,3A,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one 2-(1-Azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one (S-(R,R))-2-(1-Azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one (S-(R,R))-2-(1-Azabicyclo(2.2.2)oct-3-yl)-2,3,3A,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one 1H-Benz[de]isoquinolin-1-one, 2-(3S)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-, (3aS)- 1H-Benz(de)isoquinolin-1-one, 2-(1-azabicyclo(2.2.2)oct-3-yl)-2,3,3A,4,5,6-hexahydro-, (S-(R,R))- 1H-Benz(de)isoquinolin-1-one, 2-(1-azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-, (S-(R,R))-
CAS	135729-61-2
EINECS	1312995-182-4
Chemical Formula	C19H24N2O
Molecular Weight	296.41
inchi	InChI=1/C19H24N2O/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-21(19)17-12-20-9-7-13(17)8-10-20/h2,4,6,13,15,17H,1,3,5,7-12H2/t15-,17+/m0/s1
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Descriptions	Palonosetron Palonosetron MedChemExpress (MCE) HY-A0018 135729-61-2 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Palonosetron Palonosetron MedChemExpress (MCE) HY-A0018 135729-61-2 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Palonosetron is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). 5-HT3 Receptor \| \| \| \| \| \| \| \| \| \| [1]. Celio L, Agustoni F, Testa I, Dotti K, De Braud F.Palonosetron: an evidence-based choice in prevention of nausea and vomiting induced by moderately emetogenic chemotherapy.Tumori. 2012 May 98(3):279-86. [Content Brief] [2]. Blazer M, Phillips G, Reardon J, Efries D, Smith Y, Weatherby L, Juergens K, Rose J, Griffith N, Bekaii-Saab T.Antiemetic control with palonosetron in patients with gastrointestinal cancer receiving a fluoropyrimidine-based regimen in addition to either irinotecan or oxaliplatin: a retrospective study.Oncology. 2012 83(3):135-40. Epub 2012 Jul 18. [Content Brief] [3]. Dogan U, Yavas G, Tekinalp M, Yavas C, Ata OY, Ozdemir K.Evaluation of the acute effect of palonosetron on transmural dispersion of myocardial repolarization.Eur Rev Med Pharmacol Sci. 2012 Apr 16(4):462-8. [Content Brief] [4]. Jin Y, Sun W, Gu D, Yang J, Xu Z, Chen J.Comparative efficacy and safety of palonosetron with the first 5-HT3 receptor antagonists for the chemotherapy-induced nausea and vomiting: a meta-analysis.Eur J Cancer Care (Engl). 2012 Apr 22. [Content Brief] [5]. Clark, Robin D. Miller, Aaron B. Berger, Jacob Repke, David B. Weinhardt, Klaus K. Kowalczyk, Bruce A. Eglen, Richard M. Bonhaus, Douglas W. Lee, Chi Ho et al.2-(Quinuclidin-3-yl)pyrido[4,3-b]indol-1-ones and isoquinolin-1-ones. Potent conformationally restricted 5-HT3 receptor antagonists.J. Med. Chem., 1993, 36 (18), pp 2645-2657
Last Update	2025-04-01 14:45:47

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