(R)-Pramipexole; R-(+)-Pramipexole; KNS-760704 MedChemExpress (MCE)

Product Name	Dexpramipexole
Synonyms	DexpraMipexole Dexpramipexole (R)-Pramipexole R-(+)-Pramipexole (R)-Pramipexole Dihydrochloride R-(+)-Pramipexole Dihydrochloride (R)-4,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamine Synonyms DexpraMipexole Dexpramipexole (R)-Pramipexole R-(+)-Pramipexole (R)-Pramipexole Dihydrochloride R-(+)-Pramipexole Dihydrochloride (R)-4,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamine (R)-4,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamine Dihydrochloride Pramipexole Related Compound D (25 mg) ((R)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole)
CAS	104632-28-2
EINECS
Chemical Formula	C10H17N3S
Molecular Weight	211.33
inchi
Package	Inquiry
Price	Get quote
Descriptions	Dexpramipexole Dexpramipexole MedChemExpress (MCE) HY-17355B 104632-28-2 (R)-Pramipexole Descriptions Dexpramipexole Dexpramipexole MedChemExpress (MCE) HY-17355B 104632-28-2 (R)-Pramipexole R-(+)-Pramipexole KNS-760704 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Dexpramipexole(KNS-760704), also known as R-(+)-Pramipexole, is a neuroprotective agent and weak non-ergoline dopamine agonist. \| \| \| \| \| \| \| \| \| \| [1]. Rudnicki SA, Berry JD, Ingersoll E, et al. Dexpramipexole effects on functional decline and survival in subjects with amyotrophic lateral sclerosis in a Phase II study: subgroup analysis of demographic and clinical characteristics. Amyotroph Lateral Scler [Content Brief] [2]. Alavian KN, Dworetzky SI, Bonanni L, et al. Effects of dexpramipexole on brain mitochondrial conductances and cellular bioenergetic efficiency. Brain Res. 2012 Mar 29 1446:1-11. [Content Brief] [3]. Cudkowicz M, Bozik ME, Ingersoll EW, et al. The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis. Nat Med. 2011 Nov 20 17(12):1652-6. [Content Brief] [4]. Bozik ME, Mather JL, Kramer WG, et al. Safety, tolerability, and pharmacokinetics of KNS-760704 (dexpramipexole) in healthy adult subjects. J Clin Pharmacol. 2011 Aug 51(8):1177-85. [Content Brief] [5]. Cheah BC, Kiernan MC. Dexpramipexole, the R(+) enantiomer of pramipexole, for the potential treatment of amyotrophic lateral sclerosis. IDrugs. 2010 Dec 13(12):911-20. [Content Brief]
Supplier Website	https://www.medchemexpress.com/dexpramipexole.html
Last Update	2025-05-21 16:50:25

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