(+)-DTBZ; (+)-α-Dihydrotetrabenazine; (+)-α-DHTBZ MedChemExpress (MCE)

Product Name	[2R-(2a,3b,11bb)]-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol
Synonyms	NBI-98782 Tetrabenazine metabolite A Tetrabenazine metabolite B Tetrabenazine Related Impurity 27 NBI-98782((+)-α-Dihydrotetrabenazine) Tetrabenazine Related Impurity 27 (2R, 3R, 11bR) (2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol Synonyms NBI-98782 Tetrabenazine metabolite A Tetrabenazine metabolite B Tetrabenazine Related Impurity 27 NBI-98782((+)-α-Dihydrotetrabenazine) Tetrabenazine Related Impurity 27 (2R, 3R, 11bR) (2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol 2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, (2R,3R,11bR)- [2R-(2a,3b,11bb)]-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol
CAS	85081-18-1
EINECS
Chemical Formula	C19H29NO3
Molecular Weight	319.44
inchi
Package	10 mM * 1 mL;1 mg;5 mg;10 mg;25 mg;50 mg
Price	Get quote
Descriptions	NBI-98782 NBI-98782 MedChemExpress (MCE) HY-15793 85081-18-1 (+)-DTBZ Descriptions NBI-98782 NBI-98782 MedChemExpress (MCE) HY-15793 85081-18-1 (+)-DTBZ (+)-α-Dihydrotetrabenazine (+)-α-DHTBZ 98.56% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. NBI-98782 is a high affinity and selectivity vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki of 3 nM. NBI-98782 has antipsychotic activity. NBI-98782 (10 mg/kg, p.o., daily for 7 days) decreases basal and APDs-induced monoamine efflux in both mPFC and dSTR in male C57BL/6J mice[1]. \| \| \| \| \| \| \| \| \| \| [1]. Huang M, et al. Effects of NBI-98782, a selective vesicular monoamine transporter 2 (VMAT2) inhibitor, on neurotransmitter efflux and phencyclidine-induced locomotor activity: Relevance to tardive dyskinesia and antipsychotic action. Pharmacol Biochem Behav. 2020 Mar 190:172872. [Content Brief]
Last Update	2025-04-01 14:45:47

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