Lignocaine hydrochloride MedChemExpress (MCE)

Product Name	lidocaine hydrochloride
Synonyms	LIDOCAINE HCL Lidocaine HCl Lignocaine HCl lidocaineHydrochloride LIDOCAINE HYDROCHLORIDE lidocaine hydrochloride LIGNOCAINE HYDROCHLORIDE Synonyms LIDOCAINE HCL Lidocaine HCl Lignocaine HCl lidocaineHydrochloride LIDOCAINE HYDROCHLORIDE lidocaine hydrochloride LIGNOCAINE HYDROCHLORIDE Lidocaine hydrochloride CP2000,BP98 a-(diethylamino)-26-acetoxylidideHCl a-(diethylamino)-26-acetoxylididehydrochloride 2-(Diethylamino)-N-(2,6-dimethylphenyl)-acetamide hydrochloride Acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-, monohydrochloride 2-(diethylamino)-n-(2,6-dimethylphenyl)-acetamid monohydrochloride alpha-diethylamino-2,6-acetoxylidine hydrochloride anestacon hydrochloride duncaine hydrochloride
CAS	73-78-9
EINECS	200-803-8
Chemical Formula	C14H23ClN2O
Molecular Weight	270.8
inchi	InChI=1/C14H22N2O.ClH/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H
Package	10 mM * 1 mL;500 mg;5 g;10 g
Price	Get quote
Descriptions	Lidocaine hydrochloride Lidocaine hydrochloride MedChemExpress (MCE) HY-B0185A 73-78-9 Lignocaine hydrochloride 99.96% 4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months Descriptions Lidocaine hydrochloride Lidocaine hydrochloride MedChemExpress (MCE) HY-B0185A 73-78-9 Lignocaine hydrochloride 99.96% 4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture and light) Room temperature in continental US may vary elsewhere. Lidocaine hydrochloride (Lignocaine hydrochloride) inhibits sodium channels involving complex voltage and using dependence. Lidocaine hydrochloride decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine hydrochloride is an amide derivative and a agent to treat ventricular arrhythmia and an effective tumor-inhibitor. Lidocaine hydrochloride (Lignocaine hydrochloride) (10 nM 48 hours) decreases significantly cell proliferation[2]. Lidocaine hydrochloride (1-10 nM 24-72 hours) inhibits cell viability and achieves the most suppressing effects at the concentration of 10 nM and treatment time 48 hours[2]. Lidocaine hydrochloride (10 nM 48 hours) increases significantly the apoptotic cell rate[2]. Lidocaine hydrochloride (10 nM 48 hours) down-regulates Cyclin D1 and up-regulates p21 expression significantly[2]. Lidocaine hydrochloride (Lignocaine hydrochloride) causes completely reversible tail nerve block in rats. Mechanical nociception block produced by lidocaine has slower onset and faster recovery compared with thermal nociception block[3]. MEK ERK NF-κB \| \| \| \| \| \| \| \| \| \| [1]. Cummins TR, et al. Setting up for the block: the mechanism underlying lidocaine's use-dependent inhibition of sodium channels. J Physiol. 2007 Jul 1 582(Pt 1):11. [Content Brief] [2]. Sui H, et al. Lidocaine inhibits growth, migration and invasion of gastric carcinoma cells by up-regulation of miR-145. BMC Cancer. 2019 Mar 15 19(1):233. [Content Brief] [3]. Li Z, et al. Evaluation of the antinociceptive effects of lidocaine and bupivacaine on the tail nerves of healthy rats. Basic Clin Pharmacol Toxicol. 2013 Jul 113(1):31-6. [Content Brief]
Supplier Website	https://www.medchemexpress.com/Lidocaine-hydrochloride.html
Last Update	2025-05-21 16:50:25

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