VL285 MedChemExpress (MCE)

Product Name	VL285
Synonyms	VL285 VL-285 VL285 VL 285 (2S,4R)-4-Hydroxy-1-((S)-3-methyl-2-(1-oxoisoindolin-2-yl)butanoyl)-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (2S,4R)-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}-1-[(2S)-3-methyl-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)butanoyl]pyrrolidine-2-carboxamide Synonyms VL285 VL-285 VL285 VL 285 (2S,4R)-4-Hydroxy-1-((S)-3-methyl-2-(1-oxoisoindolin-2-yl)butanoyl)-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (2S,4R)-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}-1-[(2S)-3-methyl-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)butanoyl]pyrrolidine-2-carboxamide 2-Pyrrolidinecarboxamide, 1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (2S,4R)-
CAS	1448188-57-5
EINECS
Chemical Formula	C29H32N4O4S
Molecular Weight	532.65
inchi
Package	1 mg;5 mg;10 mg;25 mg;50 mg
Price	Get quote
Descriptions	VL285 VL285 MedChemExpress (MCE) HY-111663 1448188-57-5 98.84% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions VL285 VL285 MedChemExpress (MCE) HY-111663 1448188-57-5 98.84% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. VL285 is a potent VHL ligand with an IC50 of 0.34 μM. Treatment with VL285 attenuates the ability of HaloPROTAC3 to induce the degradation of GFP-HaloTag7[1]. VHL \| \| \| \| \| \| \| \| \| \| [1]. Buckley DL, et al. HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins. ACS Chem Biol. 2015 Aug 21 10(8):1831-7. [Content Brief]
Supplier Website	https://www.medchemexpress.com/VL285.html
Last Update	2025-05-21 16:50:25

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