Oxacillin MedChemExpress (MCE)

Product Name	OXACILLIN
Synonyms	Oxazina Bactocil OXACILLIN Penstapho UWYHMGVUTGAWSP-JKIFEVAISA-N [2S-(2,5,6)]-3,3-dimethyl-6-(methyl-3-phenylisoxaz-4-ole-carboxamide-7-oxy-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid Synonyms Oxazina Bactocil OXACILLIN Penstapho UWYHMGVUTGAWSP-JKIFEVAISA-N [2S-(2,5,6)]-3,3-dimethyl-6-(methyl-3-phenylisoxaz-4-ole-carboxamide-7-oxy-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (2S,5R,6R)-3,3-Dimethyl-6-[(5-methyl-3-phenylisoxazol-4-yl)carbonylamino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-6-[[(5-methyl-3-phenyl-4-isoxazolyl)carbonyl]amino]-7-oxo-, (2S,5R,6R)-
CAS	66-79-5
EINECS	200-635-5
Chemical Formula	C19H19N3O5S
Molecular Weight	401.44
inchi
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Descriptions	Oxacillin Oxacillin MedChemExpress (MCE) HY-B0925A 66-79-5 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Oxacillin Oxacillin MedChemExpress (MCE) HY-B0925A 66-79-5 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Oxacillin is an orally active synthetic penicillin with good bactericidal activity against staphylococci and other gram-positive pathogens. Oxacillin inhibits gram positive pathogens with MICs of 0.05, 0.09, 0.32 and 0.80 μg/mL against group A streptococci, Pneutnococci, susceptible staphylococci and penicillin-resistant staphylococci, respectively[1]. The Oxacillin-resistant strains are highly resistant to other penicillins[1]. Oxacillin (50-800 mg/kg s.c. once) shows curative dose (CD50) of 253.3 mg/kg in mice infected with Staphylococcus aureus Evans. The oral CD50 of Oxacillin is 187.2 mg/kg[2]. β-lactam \| \| \| \| \| \| \| \| \| \| [1]. KIRBY WM, et al. Oxacillin: laboratory and clinical evaluation. JAMA. 1962 Sep 1 181:739-44. [Content Brief] [2]. Yurchenco JA, et al. Nafcillin and oxacillin: comparative antistaphylococcal activity in mice. J Antibiot (Tokyo). 1976 Apr 29(4):460-5. [Content Brief]
Last Update	2025-04-01 14:45:47

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