Polyinosinic acid MedChemExpress (MCE)

Product Name	Poly I
Synonyms	Poly I POLY RL POTASSIUM SALT POLY[I] POTASSIUM SALT polyinosinicacidpot.salt 5'-Inosinic acid polymers POLYINOSINIC ACID POTASSIUM SALT POLYINOSINIC ACID TRIPOTASSIUM SALT Synonyms Poly I POLY RL POTASSIUM SALT POLY[I] POTASSIUM SALT polyinosinicacidpot.salt 5'-Inosinic acid polymers POLYINOSINIC ACID POTASSIUM SALT POLYINOSINIC ACID TRIPOTASSIUM SALT POLYINOSINIC ACID (5') POTASSIUM SALT POLYINOSINIC ACID POT. SALT, LYOPH., MR ~1200000
CAS	30918-54-8
EINECS	1592732-453-0
Chemical Formula	C10H13N4O8P
Molecular Weight	348.21
inchi
Package	Inquiry
Price	Get quote
Descriptions	Polyinosinic acid Polyinosinic acid MedChemExpress (MCE) HY-148980 30918-54-8 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Polyinosinic acid Polyinosinic acid MedChemExpress (MCE) HY-148980 30918-54-8 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Polyinosinic acid is a single stranded homonucleic acid, which is a Toll-like Receptor 3 (TLR3) ligand. Polyinosinic acid enhances cellular immune response through TLR3 and TRIF. Polyinosinic acid has potential applications in immune regulation. Polyinosinic acid (50 µg/mL, 24 h) induces the expression of CD86, CD40 and MHC II in BALB/c B cells, the expression of CD86 and CD40 in BALB/c BMDC cells[1]. Polyinosinic acid (1-25 µg/mL, 48 h) enhances the uptake of [3H] thymidine by BALB/c B cells in a dose dependent manner[1]. Polyinosinic acid (50 µg/mL, 20 h) induces BALB/c BMDC cells, macrophages to secrete TNFα and IL-12, and BALB/c B cells, BMDC cells to secrete IFN. Polyinosinic acid increases expression of MHC II, CD86 in C57Bl/6, MyD88 knockout and TLR4 knockout mouse B cells[1]. Polyinosinic acid (50 µg/mL, 48 h) increases the uptake of thymidine by C57Bl/6, MyD88 knockout and TLR4 knockout mouse B cells[1]. Polyinosinic acid (25 µg/mL and 50 µg/mL, 24 h) induces BEAS-2B cells secrete IP-10 with dose-dependent manner[1]. Polyinosinic acid (50 µg/mL, 24-48 h) regulates the expression of CD86 and thymidine uptake in B cells of TRIF+/+ and TRIF-/- mice through TRIF[1]. Polyinosinic acid (10-50 µg/mL, 20 h) increases BMDC cells derived from TLR3+/+ to secrete IFN and IFNα without affecting BMDC cells derived from TLR3-/-[1]. \| \| \| \| \| \| \| \| \| \| [1]. Marshall-Clarke S, et al. Polyinosinic acid is a ligand for toll-like receptor 3. J Biol Chem. 2007 Aug 24 282(34):24759-66. [Content Brief]
Supplier Website	https://www.medchemexpress.com/polyinosinic-acid.html
Last Update	2025-05-21 16:50:25

MedChemExpress (MCE) also provides

Thalidomide-4-O-C2-NH2

Category: Signaling Pathways
CAS: 2341840-99-9
Last Update: 2025-05-21 16:50:25

PPARα-MO-1

Category: Signaling Pathways
CAS: 810677-36-2
Last Update: 2025-05-21 16:50:25

Netupitant N-oxide

Category: Signaling Pathways
CAS: 910808-11-6
Last Update: 2025-05-21 16:50:25

MK-0812

Category: Signaling Pathways
CAS: 624733-88-6
Last Update: 2025-05-21 16:50:25

TS-011

Category: Signaling Pathways
CAS: 339071-18-0
Last Update: 2025-05-21 16:50:25

SCH 530348 sulfate

Category: Signaling Pathways
CAS: 705260-08-8
Last Update: 2025-05-21 16:50:25

BAG 956

Category: Signaling Pathways
CAS: 853910-02-8
Last Update: 2025-05-21 16:50:25

YM758

Category: Signaling Pathways
CAS: 312752-85-5
Last Update: 2025-05-21 16:50:25


Supplier Name	MedChemExpress (MCE)
Contact	sales
Tel	609-228-6898
Mobile	609-228-6898
QQ
Email	sales@medchemexpress.com; tech@medchemexpress.com
Website	https://www.medchemexpress.com/
Wechat

Request for quotation

Supplier Contact