Hydroxy-Amino-bis(PEG2-propargyl) MedChemExpress (MCE)

Product Name	Hydroxy-amino-bis(peg2-propargyl)
Synonyms	Hydroxy-Amino-(PEG2-propargyl)2;Hydroxy-amino-bis(peg2-propargyl);Hydroxy-Amino-bis(PEG2-propargyl);Ethanol, 2-[bis[2-[2-(2-propyn-1-yloxy)ethoxy]ethyl]amino]-
CAS	2100306-77-0
EINECS
Chemical Formula	C16H27NO5
Molecular Weight	313.39
inchi
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Price	Get quote
Descriptions	Hydroxy-Amino-bis(PEG2-propargyl) Hydroxy-Amino-bis(PEG2-propargyl) MedChemExpress (MCE) HY-140082 2100306-77-0 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Hydroxy-Amino-bis(PEG2-propargyl) Hydroxy-Amino-bis(PEG2-propargyl) MedChemExpress (MCE) HY-140082 2100306-77-0 Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Hydroxy-Amino-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Hydroxy-Amino-bis(PEG2-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs contain two different ligands connected by a linker one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. PEGs \| \| \| \| \| \| \| \| \| \| [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct 36:553-562 [Content Brief]
Supplier Website	https://www.medchemexpress.com/hydroxy-amino-bis-peg2-propargyl.html
Last Update	2025-05-21 16:50:25

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