Naphthazoline MedChemExpress (MCE)

Product Name	Naphazoline
Synonyms	NAFAZOLINE Naphazoline 2-(1-Naphtylmethyl)-2-imidazoline 2-(1-NAPHTHYLMETHYL)IMIDAZOLINIUM CHLORIDE 2-(1-NAPHTHYLMETHYL)-2-IMIDAZOLINE HYDROCHLORIDE 2-(Naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole Synonyms NAFAZOLINE Naphazoline 2-(1-Naphtylmethyl)-2-imidazoline 2-(1-NAPHTHYLMETHYL)IMIDAZOLINIUM CHLORIDE 2-(1-NAPHTHYLMETHYL)-2-IMIDAZOLINE HYDROCHLORIDE 2-(Naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole 1H-Imidazole, 4,5-dihydro-2-(1-naphthalenylmethyl)- 4,5-DIHYDRO-2-(1-NAPHTHYLMETHYL)-1H-IMIDAZOLE HYDROCHLORIDE
CAS	835-31-4
EINECS	212-641-5
Chemical Formula	C14H15ClN2
Molecular Weight	246.74
inchi
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Descriptions	Naphazoline Naphazoline MedChemExpress (MCE) HY-111326 835-31-4 Naphthazoline Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Naphazoline Naphazoline MedChemExpress (MCE) HY-111326 835-31-4 Naphthazoline Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Naphazoline (Naphthazoline) is a potent α-adrenergic receptor agonist. Naphazoline reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline can be used for non-bacterial conjunctivitis research. Naphazoline (0.2 mg/kg, 10 μl per eye IP, once) reduces histamine or antigen-induced conjunctival vascular hyperpermeability in mice, and reduces conjunctivitis in mice via effects on inflammation, NGF and VEGF[1]. IL-1β IL-6 IL-4 \| \| \| \| \| \| \| \| \| \| [1]. Quan L, et, al. Treatment with olopatadine and naphazoline hydrochloride reduces allergic conjunctivitis in mice through alterations in inflammation, NGF and VEGF. Mol Med Rep. 2016 Apr 13(4):3319-25. [Content Brief] [2]. Yamaguchi I, et, al. Central and peripheral adrenergic mechanisms regulating gastric secretion in the rat. J Pharmacol Exp Ther. 1977 Oct 203(1):125-31. [Content Brief]
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Last Update	2025-05-21 16:50:25

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