142994-19-2
(R)-N-FMOC-4-Chlorophenylalanine
CAS: 142994-19-2
Molecular Formula: C24H20ClNO4
142994-19-2 - Names and Identifiers
| Name | (R)-N-FMOC-4-Chlorophenylalanine |
| Synonyms | Fmoc-D-4-Chlorophe FMOC-D-4-Chlorophe Fmoc-D-Phe(4-Cl)-OH Fmoc-4-Chloro-D-Phe-OH Fmoc-4-chloro-D-phenylalani Fmoc-D-4-Chlorophenylalanine Fmoc-4-Chloro-D-phenylalanine (R)-N-FMOC-4-Chlorophenylalanine 4-Chloro-D-phenylalanine, N-FMOC protected N-Fluorenemethoxycarbonyl-D-4-Chloro Phenylalanine N-(9-FLUORENYLMETHOXYCARBONYL)-4-CHLOROPHENYL-D-ALANINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-P-CHLORO-D-PHENYLALANINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-4-CHLORO-D-PHENYLALANINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-D-4-CHLORO-PHENYLALANINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-4-CHLORO-D-PHENYLALANINE |
| CAS | 142994-19-2 |
| InChI | InChI=1/C24H20ClNO4/c25-16-11-9-15(10-12-16)13-22(23(27)28)26-24(29)30-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,26,29)(H,27,28)/t22-/m0/s1 |
| InChIKey | CQPNKLNINBUUOM-JOCHJYFZSA-N |
142994-19-2 - Physico-chemical Properties
| Molecular Formula | C24H20ClNO4 |
| Molar Mass | 421.87 |
| Density | 1.1529 (rough estimate) |
| Melting Point | 147.2 °C |
| Boling Point | 640.9±55.0 °C(Predicted) |
| Specific Rotation(α) | 30 º (c=1,DMF) |
| Flash Point | 341.4°C |
| Vapor Presure | 2.64E-17mmHg at 25°C |
| Appearance | White to white-like powder |
| Color | White |
| BRN | 8726004 |
| pKa | 3.72±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.6290 (estimate) |
| MDL | MFCD00077066 |
142994-19-2 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29242990 |
| Hazard Class | IRRITANT |
142994-19-2 - Introduction
Fmoc-D-4-Chlorophenylalanine is an organic compound with the chemical name (2S)-4-(9H-Fluoren-9-yl)methyl-2-chlorophenylalanine. Its nature, use, formulation and safety information are described below.
Nature:
Fmoc-D-4-Chlorophenylalanine is a solid with a white to yellowish color. Its molecular formula is C25H20ClNO2 and its molecular weight is 415.88g/mol. The compound is soluble in organic solvents such as dimethylsulfoxide (DMSO) and dimethylformamide (DMF), but insoluble in water.
Use:
Fmoc-D-4-chlorophenylalanine is commonly used as a protected amino acid in solid phase synthesis. It is a Fmoc protecting group derivative, the Fmoc group can be removed under acidic conditions to expose the internal amino acid. This allows it to be used as a starting amino acid in the synthesis of polypeptides and proteins.
Preparation Method:
The preparation of Fmoc-D-4-chlorophenylalanine is usually accomplished by synthetic chemical methods. A common synthesis method is to use Fmoc amino acid and 4-chlorophenylpropanol as starting materials, link them together by etherification reaction, and then reduce the amide bond to amino acid by hydrogenation reduction or other suitable method.
Safety Information:
Fmoc-D-4-Chlorophenylalanine is relatively safe under normal operating conditions, but the following matters still need to be noted:
-Use with suitable protective gloves and glasses to avoid contact with skin and eyes. In case of accidental contact, rinse the affected area immediately with plenty of water and seek medical help.
-Avoid inhaling dust or solution vapor during operation. Use should ensure a well-ventilated laboratory environment.
-Waste disposal should be carried out in accordance with local regulations and avoid random dumping.
-When using or storing Fmoc-D-4-chlorophenylalanine, please refer to the safety data sheet and instruction manual provided by the supplier for detailed information.
Nature:
Fmoc-D-4-Chlorophenylalanine is a solid with a white to yellowish color. Its molecular formula is C25H20ClNO2 and its molecular weight is 415.88g/mol. The compound is soluble in organic solvents such as dimethylsulfoxide (DMSO) and dimethylformamide (DMF), but insoluble in water.
Use:
Fmoc-D-4-chlorophenylalanine is commonly used as a protected amino acid in solid phase synthesis. It is a Fmoc protecting group derivative, the Fmoc group can be removed under acidic conditions to expose the internal amino acid. This allows it to be used as a starting amino acid in the synthesis of polypeptides and proteins.
Preparation Method:
The preparation of Fmoc-D-4-chlorophenylalanine is usually accomplished by synthetic chemical methods. A common synthesis method is to use Fmoc amino acid and 4-chlorophenylpropanol as starting materials, link them together by etherification reaction, and then reduce the amide bond to amino acid by hydrogenation reduction or other suitable method.
Safety Information:
Fmoc-D-4-Chlorophenylalanine is relatively safe under normal operating conditions, but the following matters still need to be noted:
-Use with suitable protective gloves and glasses to avoid contact with skin and eyes. In case of accidental contact, rinse the affected area immediately with plenty of water and seek medical help.
-Avoid inhaling dust or solution vapor during operation. Use should ensure a well-ventilated laboratory environment.
-Waste disposal should be carried out in accordance with local regulations and avoid random dumping.
-When using or storing Fmoc-D-4-chlorophenylalanine, please refer to the safety data sheet and instruction manual provided by the supplier for detailed information.
Last Update：2024-04-10 22:29:15
Supplier List
Featured ProductsSpot supply
Product Name: Fmoc-4-Chloro-D-Phe-OH Visit Supplier Webpage Request for quotationCAS: 142994-19-2
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: Fmoc-D-Phe(4-Cl)-OH Request for quotationCAS: 142994-19-2
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Product Name: Fmoc-D-4-Chlorophenylalanine Request for quotation
CAS: 142994-19-2
Tel: +86 0512-69209928
Email: wuhao@highfine.com
merry@highfine.com
chenmengqi@highfine.com
QQ: 4006286883
CAS: 142994-19-2
Tel: +86 0512-69209928
Email: wuhao@highfine.com
merry@highfine.com
chenmengqi@highfine.com
QQ: 4006286883
Spot supply
Product Name: (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-chlorophenyl)propanoic acid Visit Supplier Webpage Request for quotationCAS: 142994-19-2
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Fmoc-4-Chloro-D-Phe-OH Visit Supplier Webpage Request for quotationCAS: 142994-19-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: FMOC-D-4-Chlorophe Visit Supplier Webpage Request for quotationCAS: 142994-19-2
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: Fmoc-D-4-Chlorophe Visit Supplier Webpage Request for quotation
CAS: 142994-19-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 142994-19-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Featured ProductsSpot supply
Product Name: Fmoc-4-Chloro-D-Phe-OH Visit Supplier Webpage Request for quotationCAS: 142994-19-2
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: Fmoc-D-Phe(4-Cl)-OH Request for quotationCAS: 142994-19-2
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Product Name: Fmoc-D-4-Chlorophenylalanine Request for quotation
CAS: 142994-19-2
Tel: +86 0512-69209928
Email: wuhao@highfine.com
merry@highfine.com
chenmengqi@highfine.com
QQ: 4006286883
CAS: 142994-19-2
Tel: +86 0512-69209928
Email: wuhao@highfine.com
merry@highfine.com
chenmengqi@highfine.com
QQ: 4006286883
Spot supply
Product Name: (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-chlorophenyl)propanoic acid Visit Supplier Webpage Request for quotationCAS: 142994-19-2
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Fmoc-4-Chloro-D-Phe-OH Visit Supplier Webpage Request for quotationCAS: 142994-19-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: FMOC-D-4-Chlorophe Visit Supplier Webpage Request for quotationCAS: 142994-19-2
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: Fmoc-D-4-Chlorophe Visit Supplier Webpage Request for quotation
CAS: 142994-19-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 142994-19-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History