163217-43-4
Fmoc-p-azido-Phe-OH
CAS: 163217-43-4
Molecular Formula: C24H20N4O4
163217-43-4 - Names and Identifiers
163217-43-4 - Physico-chemical Properties
| Molecular Formula | C24H20N4O4 |
| Molar Mass | 428.44 |
| Storage Condition | -15°C |
163217-43-4 - Introduction
Fmoc-p-azido-Phe-OH is an organic compound commonly used in solid-phase synthesis as an amino acid protecting group.
Properties: Fmoc-p-azido-Phe-OH is a white solid with good solubility. It is readily soluble in organic solvents, such as dimethyl sulfoxide (DMSO), dichloromethane (DCM), etc.
Purpose: Fmoc-p-azido-Phe-OH is mainly used for peptide synthesis in solid phase synthesis. It can act as an amino acid protecting group, protecting the amino acids in the polypeptide chain from side reactions or unwanted cross-reactions during synthesis.
Preparation method: The Fmoc-p-azido-Phe-OH can be prepared by a chemical synthesis method. The specific procedure involves first preparing 4-azidophenyl propanol and then reacting it with Fmoc-chloroformate to form a Fmoc-p-azido-Phe-OH under appropriate conditions.
Safety Information: Fmoc-p-azido-Phe-OH are generally less toxic under normal conditions of use. However, it is still a chemical and should be handled with caution. Wear appropriate personal protective equipment, such as gloves and safety glasses, when in use. At the same time, it should be operated in a well-ventilated laboratory environment to avoid inhalation or contact with high concentrations of gases or liquids. In case of accidental contact or ingestion, seek medical attention immediately. When using and storing, please follow the relevant laboratory safety regulations and instructions.
Properties: Fmoc-p-azido-Phe-OH is a white solid with good solubility. It is readily soluble in organic solvents, such as dimethyl sulfoxide (DMSO), dichloromethane (DCM), etc.
Purpose: Fmoc-p-azido-Phe-OH is mainly used for peptide synthesis in solid phase synthesis. It can act as an amino acid protecting group, protecting the amino acids in the polypeptide chain from side reactions or unwanted cross-reactions during synthesis.
Preparation method: The Fmoc-p-azido-Phe-OH can be prepared by a chemical synthesis method. The specific procedure involves first preparing 4-azidophenyl propanol and then reacting it with Fmoc-chloroformate to form a Fmoc-p-azido-Phe-OH under appropriate conditions.
Safety Information: Fmoc-p-azido-Phe-OH are generally less toxic under normal conditions of use. However, it is still a chemical and should be handled with caution. Wear appropriate personal protective equipment, such as gloves and safety glasses, when in use. At the same time, it should be operated in a well-ventilated laboratory environment to avoid inhalation or contact with high concentrations of gases or liquids. In case of accidental contact or ingestion, seek medical attention immediately. When using and storing, please follow the relevant laboratory safety regulations and instructions.
Last Update：2024-04-09 21:11:58
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CAS: 163217-43-4
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CAS: 163217-43-4
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