352535-85-4

352535-85-4 - Names and Identifiers

Name	(2-chloro-6-fluoro-3-methylphenyl)boronic acid
Synonyms	2-Chloro-6-fluoro-3-methylBenzeneBoronicacid 2-Chloro-6-fluoro-3-methylbenzeneboronic acid (2-chloro-6-fluoro-3-methylphenyl)boronic acid 2-Chloro-6-fluoro-3-methylphenylboronic acid(contains varying amounts of Anhydride)
CAS	352535-85-4
InChI	InChI=1/C7H7BClFO2/c1-4-2-3-5(9)6(7(4)10)8(11)12/h2-3,11-12H,1H3

352535-85-4 - Physico-chemical Properties

Molecular Formula	C7H7BClFO2
Molar Mass	188.39
Density	1.35g/cm³
Melting Point	150-154°C(lit.)
Boling Point	323.3°C at 760 mmHg
Flash Point	149.3°C
Vapor Presure	0.000108mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.528

352535-85-4 - Risk and Safety

Hazard Symbols	Xi - Irritant
WGK Germany	3

352535-85-4 - Introduction

boronic acid is an organic boron compound with the chemical formula C7H7BClF.

Properties:(2-chloro-6-fluoro-3-methylphenyl)boronic acid is a white or light yellow solid, soluble in organic solvents such as ethanol and dichloromethane. It is almost insoluble in hot water.

Use: This compound can be used as an important reagent in organic synthesis. It has a wide range of applications in the synthesis of lead compounds, drug research and pesticide development. It is often used as a boron-based reagent in organic synthesis reactions such as Suzuki reaction, Heck reaction and fluorination reaction.

Preparation method:(2-chloro-6-fluoro-3-methylphenyl)boronic acid can be prepared by reacting phenyl boronic acid with the corresponding halogenated alkyl compound under palladium catalysis.

Safety Information: This compound may be irritating to the eyes, skin and respiratory system and may be a potential health hazard. Wear appropriate protective equipment during use and ensure that you operate in a well-ventilated environment.

Last Update：2024-04-09 02:00:45