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52438-12-7

Isobutyrylshikonin

CAS: 52438-12-7

Molecular Formula: C20H22O6

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52438-12-7 - Names and Identifiers

Name Isobutyrylshikonin
Synonyms Isobutylshikonin
ISOBUTYRYLSHIKONIN
Isobutyrylshikonin
Isobutyroylshikonin
5,8-DIHYDROXY-2-(1-ISOBUTYRYLOXY-4-METHYL-3-PENTENYL)-1,4-NAPHTHALENEDIONE
2-[1-(Isobutyryloxy)-4-methyl-3-pentenyl]-5,8-dihydroxy-1,4-naphthoquinone
(R)-2-Methyl-propanoic acid 1-(1,4-dihydro-5,8-dihydroxy-1,4-dioxo-2-naphthalenyl)-4-methyl-3-pentenyl ester
2-Methylpropanoic acid (R)-1-[(1,4-dioxo-5,8-dihydroxy-1,4-dihydronaphthalene)-2-yl]-4-methyl-3-pentenyl ester
CAS 52438-12-7
EINECS 932-567-3

52438-12-7 - Physico-chemical Properties

Molecular FormulaC20H22O6
Molar Mass358.39
Density1.269±0.06 g/cm3(Predicted)
Melting Point88 °C
Boling Point561.9±50.0 °C(Predicted)
Specific Rotation(α)+125 (EtOH)
Solubility Insuluble (5.4E-3 g/L) (25 °C)
AppearancePowder
pKa7.05±0.20(Predicted)
Storage Condition2-8℃
MDLMFCD00144512
Physical and Chemical PropertiesSoluble in methanol, ethanol, DMSO and other organic solvents.

52438-12-7 - Reference

Reference
Show more
1. Enke, Zheng, Yi, ya, Liu, Jie: Li, Nong, Zheng, Jian, MA, Shuangcheng. Determination of eight hydroxynaphthoquinones in different parts of arnebia euchroma by HPLC [J]. Chinese Journal of Traditional Chinese Medicine, 2017, 42(13):2532-2537.
2. Li, Jing, Li, Yao, Lei, Yu, Jian, et al. Study on quality control of arnebia euchroma by one-Test multi-evaluation method combined with characteristic chromatogram [J]. Journal of Pharmaceutical Analysis 2020(7):1209-1216.
3. Zhong Yu, Zheng Xuebao, Cai kangrong, Huang Qionglin, Ye Hua, Huang Zhen, Wang Yongsheng, Zhu Yuzhen. Isobutyrylshikonin inhibits the proliferation of colon cancer cells via PI3K/Akt/m-TOR pathway [J]. Chinese Journal of Traditional Chinese Medicine, 2018,43(11):2358-2364.
4. Wang Ruishan, Zhou Li, Wang Sheng. Study on the establishment and effect of two CYP450 gene interference hairy root system in Xinjiang [J]. Chinese Journal of Traditional Chinese Medicine, Volume 45, 202014, pages 3422-3431, MEDLINE ISTIC PKU CSCD CA BP, 2020.
5. Dong Na, Gao Zhao Jun, Qu Xiaolan, et al. Simultaneous determination of five naphthoquinones in arnebia euchroma by HPLC [J]. Journal of Taishan Medical College, 2019, 40(05):336-338.
6. Gao Zhao-jun, Liu qiue, Qu Xiaolan, etc. Comparative study on HPLC fingerprints of arnebia euchroma and arnebia euchroma in Taishan [J]. China Modern Applied Pharmacy, 2019, 036(010):1193-1196.
7. [IF = 1.312] Qi Zhang et al."Rapid and sensitive determination of shikonin and its derivatives in the roots of Arnebia euchroma (Royle) Johnst using matrix solid-phase dispersion extraction and ultrahigh-performance liquid chromatography with photodiode array detecto

52438-12-7 - Reference Information

biological activity Isobutylshikonin is shikonin pigment derived from hairy root culture of Lithospermum canescens.
chemical properties soluble in methanol, ethanol, DMSO and other organic solvents.
use isobutyryl shikonin has anti-tumor, antibacterial, anti-inflammatory and analgesic effects.
Last Update:2024-04-09 20:52:54
52438-12-7
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Shanghai Amole Biotechnology Co., Ltd.
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Product Name: Isobutyrylshikonin Request for quotation
CAS: 52438-12-7
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
Shanghai Macklin Biochemical Co., Ltd
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Product Name: Isobutyrylshikonin Visit Supplier Webpage Request for quotation
CAS: 52438-12-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
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Product Name: Isobutyrylshikonin Visit Supplier Webpage Request for quotation
CAS: 52438-12-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
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CAS: 52438-12-7
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
Shanghai Yuanye Bio-Technology Co., Ltd.
Spot supply
Product Name: Isobutyrylshikonin Visit Supplier Webpage Request for quotation
CAS: 52438-12-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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