毛蕊异黄酮-7-O-BETA-D-葡萄糖苷
毛蕊异黄酮苷(calycosin-7-o-beta-d-glucoside)
CAS: 20633-67-4
化学式: C22H22O10
| 中文名 | 毛蕊异黄酮苷 |
| 英文名 | calycosin-7-o-beta-d-glucoside |
| 别名 | 毛蕊异黄酮苷 毛蕊异黄酮葡萄糖苷 毛蕊异黄酮苷(标准品) 毛蕊异黄酮-7-O-葡萄糖苷 毛蕊异黄酮-7-O-Β-D葡萄糖苷 毛蕊异黄酮-7-O-B-D-吡喃葡萄糖 毛蕊异黄酮-7-O-BETA-D-葡萄糖苷 |
| 英文别名 | CS-2023 CALYCOSIN 7-O-GLUCOSIDE Calycosin 7-O-Glucoside calycosin-o-glucopyranoside calycosin-7-O-β-D-glucoside Calycosin-7-O-beta-D-glucoside calycosin-7-o-beta-d-glucoside Calycosin-7-glucoside 20633-67-4 Calycosin-7-O-b-D-glucopyranoside 3',7-Dihydroxy-4'-Methoxyisoflavone-7-beta-D-glucopyranoside 3-(3-Hydroxy-4-methoxyphenyl)-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside 4H-1-benzopyran-4-one, 7-(beta-D-glucopyranosyloxy)-3-(3-hydroxy-4-methoxyphenyl)- |
| CAS | 20633-67-4 |
| 化学式 | C22H22O10 |
| 分子量 | 446.41 |
| InChI | InChI=1/C22H22O10/c1-29-15-5-2-10(6-14(15)24)13-9-30-16-7-11(3-4-12(16)18(13)25)31-22-21(28)20(27)19(26)17(8-23)32-22/h2-7,9,17,19-24,26-28H,8H2,1H3/t17-,19-,20+,21-,22-/m1/s1 |
| 密度 | 1.545 |
| 熔点 | 220 - 228°C |
| 沸点 | 745.2±60.0 °C(Predicted) |
| 闪点 | 262°C |
| 蒸汽压 | 2.51E-23mmHg at 25°C |
| 溶解度 | DMSO (微溶) 、甲醇 (微溶) |
| 折射率 | 1.674 |
| 酸度系数 | 9.48±0.10(Predicted) |
| 存储条件 | Inert atmosphere,Room Temperature |
| 外观 | 固体 |
| 颜色 | Pale Beige |
| 物化性质 | 白色结晶粉末，溶于甲醇乙醇，来源于黄芪根茎。 |
| MDL号 | MFCD08061493 |
| 体外研究 | Calycosin-7-O-β-D-glucoside (2 μM; 6 hours) remarkably inhibits the expression and activities of MMPs, and secures the expression of cav-1 and tight junction proteins in the microvessels isolated from ischemic rat cortex. |
| 体内研究 | Calycosin-7-O-β-D-glucoside (intraperitoneal injection; 26.8 mg/kg; 14 days) significantly reduces infarct volume, histological damage and BBB permeability in the in vivo MCAO ischemia-reperfusion rat model. Animal Model: Middle cerebral artery occlusion (MCAO) male adult Sprague-Daweley rats Dosage: 26.8 mg/kg Administration: Intraperitoneal injection; 26.8 mg/kg; 14 days Result: Exhibited neuroprotective effects in rats. |
| 海关编号 | 2932996560 |
| 上游原料 | BETA-D-葡萄糖 |
| 参考资料 展开查看 | 1. 黎映琼 蔡庆群 苏志强 等. 不同产地黄芪根 茎 叶中4种异黄酮类成分的比较及其聚类分析[J]. 现代中药研究与实践 2020 v.34;No.173(02):69-73. 2. 石晓倩, 何玲, 刘雪,等. 新安名方脑络欣通HPLC指纹图谱研究[J]. 辽宁中医药大学学报, 2020, v.22;No.191(03):40-44. 3. 赵晓莉, 潘鹏, 周乐,等. 毛蕊异黄酮葡萄糖苷大鼠在体肠吸收动力学的研究[J]. 南京中医药大学学报, 2012, 28(006):552-554. 4. 赵晓莉, 刘玲, 狄留庆,等. 毛蕊异黄酮葡萄糖苷对升麻素苷及其苷元大鼠体内药代动力学特征的影响研究[J]. 中国中药杂志, 2014, 39(23):4669. 5. 张星, 陆兔林, 毛春芹,等. 补阳还五汤质量标准研究[J]. 中成药, 2013, 35(003):529-533. 6. 袁菊丽, 刘东玲, 黄钰芳. 超声提取红芪总黄酮工艺及其抗氧化活性的研究[J]. 中兽医医药杂志, 2019, 038(002):53-56. 7. 田湾湾, 钟琳瑛, 张琦,等. 车前子酒炙工艺优选及其不同炮制品对比研究[J]. 天津中医药, 2020, v.37(02):106-112. 8. 刘玲, 赵晓莉, 狄留庆,等. 采用体外肠道菌群实验研究防风对黄芪中毛蕊异黄酮葡萄糖苷代谢的影响[J]. 南京中医药大学学报, 2015, 000(002):170-173. 9. 李丽, 郜玉钢, 赵丽,等. 黄芪营养生长期茎叶毛蕊异黄酮苷和黄芪甲苷含量测定[J]. 辽宁中医杂志, 2014, 041(009):1942-1944. 10. 侯美如, 尹珺伊, 王岩,等. 黄芪发酵前后黄酮含量及指纹图谱比较研究[J]. 中国兽药杂志, 2018, v.52(05):52-58. 11. 李欣, 卓冰雨, 祁晓娟,等. 黄芪异黄酮含量与气候因子的灰色关联度和通径分析[J]. 中国中药杂志 2020年45卷14期, 3407-3413页, MEDLINE ISTIC PKU CSCD CA BP, 2020. 12. 王艺璇 李海涛 刘顺 等. 参葵通脉颗粒的质量标准研究[J]. 中药新药与临床药理 2020年31卷8期 984-989页 ISTIC PKU CSCD CA 2020. 13. 田文仓. 不同生长年限及采收期子洲黄芪鉴别特征及其质量、产量差异分析[D].北京中医药大学,2020. 14. 孙乐,吴鹏,王春艳,张学兰,金玉翠,刘海滨.黄芪饮片炮制工艺优选[J].时珍国医国药,2020,31(07):1616-1619. 15. 孙秀蕊,魏桂杰,王宏雅,赵雯雯,张哲,张婷,魏锋,张玉杰.基于外观性状和内在成分的黄芪药材质量等级评价[J].中国中药杂志,2021,46(04):966-971. 16. 张丽,卞晓坤,赵秋龙,钱大玮,郭盛,严辉,欧阳臻,赵建军,段金廒.基于多元成分的黄芪药材产地现代干燥加工方法[J].中国现代中药,2020,22(10):1684-1688. 17. 毛文点,庹玲玲,齐文续,苏睿智,邓常清,邹龙.黄芪-当归不同配伍对其6种主要有效成分溶出的影响[J].湖南中医药大学学报,2021,41(03):350-354. 18. Wang, Lingdi, et al. "Danggui Buxue Tang Rescues Folliculogenesis and Ovarian Cell Apoptosis in Rats with Premature Ovarian Insufficiency." Evidence-Based Complementary and Alternative Medicine 2021 (2021).https://doi.org/10.1155/2021/6614302 19. Peng-Peng, L. I. U., et al. "Metabolomics analysis and rapid identification of changes in chemical ingredients in crude and processed Astragali Radix by UPLC-QTOF-MS combined with novel informatics UNIFI platform." Chinese journal of natural medicines 16.9 20. [IF=4.759] Yuping Zhang et al."On-line surface plasmon resonance-high performance liquid chromatography–tandem mass spectrometry for analysis of human serum albumin binders from Radix Astragali."J Chromatogr A. 2013 Jun;1293:92 21. [IF=4.411] Liangliang Liu et al."Rapid Screening and Identification of BSA Bound Ligands from Radix astragali Using BSA Immobilized Magnetic Nanoparticles Coupled with HPLC-MS."Molecules. 2016 Nov;21(11):1471 22. 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毛蕊异黄酮-7-O-BETA-D-葡萄糖苷 - 简介
毛蕊异黄酮苷，也被称为毛蕊素-7-O-葡萄糖苷，是一种天然的黄酮类化合物。
毛蕊异黄酮苷具有多种生物活性，包括抗氧化、抗炎、抗菌、抗肿瘤等作用。
毛蕊异黄酮苷可以通过萃取和纯化天然植物材料而得到。常见的来源包括毛蕊素兰科植物和透明老传子纲植物的根部。制法一般包括提取、浸膏、制粉、分离和纯化等步骤。
毛蕊异黄酮苷具有多种生物活性，包括抗氧化、抗炎、抗菌、抗肿瘤等作用。
毛蕊异黄酮苷可以通过萃取和纯化天然植物材料而得到。常见的来源包括毛蕊素兰科植物和透明老传子纲植物的根部。制法一般包括提取、浸膏、制粉、分离和纯化等步骤。
最后更新：2024-04-10 22:29:15
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产品名: 毛蕊异黄酮苷(10mM in DMSO,无菌) 去供应商网站查看 询盘CAS: IC00401
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提供多种规格现货供应
产品名: 毛蕊异黄酮苷(10mM in DMSO,无菌) 去供应商网站查看 询盘CAS: IC00401
产地: 北京
包装: 1ml/瓶
规格: IC00401-1ml
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 17801761073(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 17801761073
产品描述: 索莱宝直销,欢迎来询
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