2-(1-methylethylidene)-hydrazinecarboxamid
Acetonesemicarbazone
CAS: 110-20-3
Molecular Formula: C4H9N3O
2-(1-methylethylidene)-hydrazinecarboxamid - Names and Identifiers
| Name | Acetonesemicarbazone |
| Synonyms | AURORA KA-350 Acetonesemicarbazone Acetone semicarbazon Acetone semicarbazone Acetone Semecarbazone ACETONE SEMICARBAZONE 2-Propanonesemicarbazone 2-Propanone semicarbazone 2-(propan-2-ylidene)hydrazinecarboxamide 2-(1-methylethylidene)-hydrazinecarboxamid Hydrazinecarboxamide, 2-(1-methylethylidene)- |
| CAS | 110-20-3 |
| EINECS | 203-746-7 |
| InChI | InChI=1/C4H9N3O/c1-3(2)6-7-4(5)8/h1-2H3,(H3,5,7,8) |
2-(1-methylethylidene)-hydrazinecarboxamid - Physico-chemical Properties
| Molecular Formula | C4H9N3O |
| Molar Mass | 115.13 |
| Density | 1.1906 (rough estimate) |
| Melting Point | 189-190°C |
| Boling Point | 215.41°C (rough estimate) |
| Appearance | powder to crystal |
| Color | White to Light yellow |
| Merck | 14,8444 |
| BRN | 970110 |
| pKa | 12.31±0.46(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.5700 (estimate) |
| MDL | MFCD00014785 |
| Physical and Chemical Properties | White powder. Melting point 188 °c. Soluble in alcohol, ether and hot water, slightly soluble in water. |
| Use | An intermediate used in the production of the drug furantin. |
2-(1-methylethylidene)-hydrazinecarboxamid - Risk and Safety
| Risk Codes | 22 - Harmful if swallowed |
| Safety Description | S22 - Do not breathe dust. S36/37 - Wear suitable protective clothing and gloves. S36 - Wear suitable protective clothing. |
| RTECS | AL7175000 |
| TSCA | Yes |
| HS Code | 38220090 |
| Toxicity | LD50 ivn-mus: 90 mg/kg JPETAB 122,110,58 |
2-(1-methylethylidene)-hydrazinecarboxamid - Nature
Open Data Verified Data
white powder. Melting point 188 °c. Slightly soluble in water, soluble in alcohol, ether and hot water.
Last Update：2024-01-02 23:10:35
2-(1-methylethylidene)-hydrazinecarboxamid - Preparation Method
Open Data Verified Data
with hydrazine hydrate and urea as raw materials, the condensation reaction was carried out at 100 ° C. To obtain semicarbazide, and then condensation with acetone at 65~72, the crude product of acetone urethane was prepared, and the refined product was obtained.
Last Update：2022-01-01 10:36:43
2-(1-methylethylidene)-hydrazinecarboxamid - Introduction
Soluble in alcohol, ether and hot water, slightly soluble in water.
Last Update：2022-10-16 17:11:58
2-(1-methylethylidene)-hydrazinecarboxamid - Use
Open Data Verified Data
This product is used as an intermediate for the production of drug furandantin.
Last Update：2022-01-01 10:36:43
2-(1-methylethylidene)-hydrazinecarboxamid - Safety
Open Data Verified Data
This product has low toxicity. Protection according to general chemical regulations.
Last Update：2022-01-01 10:36:43
2-(1-methylethylidene)-hydrazinecarboxamid - Reference Information
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| use | this product is used to produce an intermediate for the drug furantin. |
| production method | hydrazine hydrate and urea are used as raw materials to obtain semicarbazide liquid, which is combined with acetone to refine the finished product. Hydrazine hydrate was mixed with urea, heated to 97-104 ℃, and refluxed for 6-7h. Cool to 45°C and filter to obtain semicarbazide solution. Cold the filtrate to 25 ℃, add acetone, naturally raise the temperature to 50-60 ℃, and keep the temperature for 1h. Cool to below 20 ℃, filter, and dry the filter cake to obtain acetone ammonia urea. The weight ratio is: hydrazine hydrate (40%): urea: acetone = 1:0.67:0.56. 90% yield. As an intermediate, the appearance is white powder, melting point 185-189 ℃. Raw material consumption quota: hydrazine hydrate (40%)300 kg/t, urea (industrial products) 870 kg/t, acetone (industrial products) 720 kg/t. |
| category | toxic substances |
| toxicity classification | poisoning |
| acute toxicity | vein-mouse LD50: 90 mg/kg |
| flammability hazard characteristics | flammability; heating decomposition releases toxic nitrogen oxide smoke |
| storage and transportation characteristics | warehouse ventilation and low temperature drying |
| fire extinguishing agent | dry powder, foam, sand, carbon dioxide, mist water |
Last Update：2024-04-10 22:29:15
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CAS: 110-20-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: Acetone semicarbazone Visit Supplier Webpage Request for quotationCAS: 110-20-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Acetone semicarbazone Visit Supplier Webpage Request for quotationCAS: 110-20-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: Acetone semicarbazone Visit Supplier Webpage Request for quotation
CAS: 110-20-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 110-20-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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View History
2-(1-methylethylidene)-hydrazinecarboxamid
Potassium ferrocyanide trihyrate
Hydrazomethane
2-[4-(Methylthio)benzoyl]-2-(4-morpholinyl)propane
13446-53-2
硫
phosphorus pentoxidedessicant
Dodocyl gallate
5204-74-0
5-fluoro-o-anisidine
Potassium ferrocyanide trihyrate
Hydrazomethane
2-[4-(Methylthio)benzoyl]-2-(4-morpholinyl)propane
13446-53-2
硫
phosphorus pentoxidedessicant
Dodocyl gallate
5204-74-0
5-fluoro-o-anisidine