21156-44-5

21156-44-5 - Names and Identifiers

Name	(2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid
Synonyms	(4R)-4-Fluor-L-prolin (4R)-4-Fluoro-L-proline Proline, 4-fluoro-,trans- (2S,4R)-4-fluoro-2-proline L-proline, 4-fluoro-, (4R)- Proline, 4-fluoro-, trans- (8CI) trans-4-Fluoropyrrolidine-2-carboxylic acid (2S,4R)-4-Fluoro-2-pyrrolidinecarboxylic acid (2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid (2S,4R)-4-Fluoro-Pyrrolidine-2-Carboxylic Acid
CAS	21156-44-5
InChI	InChI=1/C5H8FNO2/c6-3-1-4(5(8)9)7-2-3/h3-4,7H,1-2H2,(H,8,9)/t3-,4+/m1/s1

21156-44-5 - Physico-chemical Properties

Molecular Formula	C5H8FNO2
Molar Mass	133.12
Density	1.30±0.1 g/cm3(Predicted)
Boling Point	265.1±40.0 °C(Predicted)
Flash Point	114.133°C
Vapor Presure	0.003mmHg at 25°C
pKa	1.88±0.40(Predicted)
Storage Condition	2-8°C
Refractive Index	1.473

21156-44-5 - Introduction

(2S,4R)-acid is a chiral organic compound with the chemical formula c99% hno₂ F. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: White solid
-Solubility: Soluble in water and some organic solvents
-Melting point: About 104-106 ° C
-optical rotation: with optical properties, under certain conditions can make polarized light produce optical rotation effect

Use:
-As a chiral catalyst in organic synthesis, it can be used to synthesize other chiral compounds
-For the preparation of drugs and bioactive molecules

Method:
(2S,4R)-the preparation method of acid is more complicated and needs to be obtained by chemical synthesis. A commonly used synthesis method is to determine the chiral degree purity by Nuclear Magnetic Hydrogen Spectroscopy and to synthesize by organic synthesis methods.

Safety Information:
-Organic compounds are generally toxic and need to follow laboratory safety practices when used.
-Toxicity data are limited, so care should be taken to avoid skin contact and inhalation.
-in handling and storage should be careful to avoid contact with strong oxidants, strong acids and other substances.

When using or handling this compound, please follow laboratory safety practices and consult professional chemists for guidance.

Last Update：2024-04-09 20:49:11