7-CHLOROQUINAZOLIN-4-OL
7-chloroquinazolin-4(1H)-one
CAS: 31374-18-2
Molecular Formula: C8H5ClN2O
7-CHLOROQUINAZOLIN-4-OL - Names and Identifiers
| Name | 7-chloroquinazolin-4(1H)-one |
| Synonyms | AFA-IM C 7-CHLORO-4-QUINAZOLINOL 7-CHLOROQUINAZOLIN-4-OL 7-chloroquinazolin-4-ol 7-Chloroquinazolin-4-one 4-quinazolinol, 7-chloro- 7-Chloro-4(3H)-quinazolone 7-chloroquinazolin-4(1H)-one 7-CHLORO-4(1H)-QUINAZOLINONE 7-Chloroquinazolin-4(3H)-one 7-chloro-1H-quinazolin-4-one 7-CHLORO-4-HYDROXYQUINAZOLINE 4(3H)-Quinazolinone, 7-chloro- 7-Chloro-4-hydroxyquinazoline 7-CHLORO-3,4-DIHYDROQUINAZOLIN-4-ONE |
| CAS | 31374-18-2 |
| EINECS | 207-219-2 |
| InChI | InChI=1/C8H5ClN2O/c9-5-1-2-6-7(3-5)10-4-11-8(6)12/h1-4H,(H,10,11,12) |
7-CHLOROQUINAZOLIN-4-OL - Physico-chemical Properties
| Molecular Formula | C8H5ClN2O |
| Molar Mass | 180.59 |
| Density | 1.50±0.1 g/cm3(Predicted) |
| Melting Point | 251-253 °C |
| Boling Point | 331.7±44.0 °C(Predicted) |
| Flash Point | 171.454°C |
| Vapor Presure | 0mmHg at 25°C |
| pKa | 0.36±0.20(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.71 |
7-CHLOROQUINAZOLIN-4-OL - Introduction
7-chloroquinazolin-4(1H)-one(7-chloroquinazolin-4(1H)-one) is an organic compound with the chemical formula C8H5ClN2O. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 7-chloroquinazolin-4(1H)-one is a white solid.
-Melting point: Its melting point range is usually between 150-153°C.
-Solubility: 7-chloroquinazolin-4(1H)-one has limited solubility in common organic solvents.
Use:
-Drug: 7-chloroquinazolin-4(1H)-one can be used as an intermediate for the synthesis of biologically active compounds, such as drugs or pesticides.
Method:
The preparation of 7-chloroquinazolin-4(1H)-one can usually be completed by the following steps:
1. Pyridine and acetone anhydride react to generate β-pyridyl pyruvate.
2. Under the catalysis of hydrogen chloride, β-pyridyl pyruvate and stannous bromide react to generate 7-bromo -4(3H)-quinazolinone.
3. Finally, 7-chloroquinazolin-4(1H)-one can be obtained by treating 7-bromo-4 (3H)-quinazolinone with copper chloride.
Safety Information:
- 7-chloroquinazolin-4(1H)-one is an organic compound with certain safety risks. During use, appropriate laboratory safety measures are required, including wearing protective gloves and eyes, and operating in well-ventilated conditions.
-It may cause irritation and harm to the skin, eyes and respiratory tract, so avoid contact with the skin and avoid inhaling its dust or gas.
-Be careful in handling and storage to avoid contact with substances such as oxidants and strong acids to prevent dangerous situations such as fire or explosion.
-Seek medical help immediately in case of any accident or discomfort.
Nature:
-Appearance: 7-chloroquinazolin-4(1H)-one is a white solid.
-Melting point: Its melting point range is usually between 150-153°C.
-Solubility: 7-chloroquinazolin-4(1H)-one has limited solubility in common organic solvents.
Use:
-Drug: 7-chloroquinazolin-4(1H)-one can be used as an intermediate for the synthesis of biologically active compounds, such as drugs or pesticides.
Method:
The preparation of 7-chloroquinazolin-4(1H)-one can usually be completed by the following steps:
1. Pyridine and acetone anhydride react to generate β-pyridyl pyruvate.
2. Under the catalysis of hydrogen chloride, β-pyridyl pyruvate and stannous bromide react to generate 7-bromo -4(3H)-quinazolinone.
3. Finally, 7-chloroquinazolin-4(1H)-one can be obtained by treating 7-bromo-4 (3H)-quinazolinone with copper chloride.
Safety Information:
- 7-chloroquinazolin-4(1H)-one is an organic compound with certain safety risks. During use, appropriate laboratory safety measures are required, including wearing protective gloves and eyes, and operating in well-ventilated conditions.
-It may cause irritation and harm to the skin, eyes and respiratory tract, so avoid contact with the skin and avoid inhaling its dust or gas.
-Be careful in handling and storage to avoid contact with substances such as oxidants and strong acids to prevent dangerous situations such as fire or explosion.
-Seek medical help immediately in case of any accident or discomfort.
Last Update：2024-04-09 21:00:56
Supplier List
Featured Products
Product Name: 7-Chloro-4-quinazolinol Request for quotationCAS: 31374-18-2
Tel: +86 0512-68417696
Email: chenmengqi@highfine.com
wuhao@highfine.com
merry@highfine.com
QQ: 4006286883
Spot supply
Product Name: 7-chloroquinazolin-4-ol Visit Supplier Webpage Request for quotationCAS: 31374-18-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 7-Chloro-1H-quinazolin-4-one Visit Supplier Webpage Request for quotationCAS: 31374-18-2
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: 7-CHLORO-4-QUINAZOLINOL Visit Supplier Webpage Request for quotation
CAS: 31374-18-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 31374-18-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Featured Products
Product Name: 7-Chloro-4-quinazolinol Request for quotationCAS: 31374-18-2
Tel: +86 0512-68417696
Email: chenmengqi@highfine.com
wuhao@highfine.com
merry@highfine.com
QQ: 4006286883
Spot supply
Product Name: 7-chloroquinazolin-4-ol Visit Supplier Webpage Request for quotationCAS: 31374-18-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 7-Chloro-1H-quinazolin-4-one Visit Supplier Webpage Request for quotationCAS: 31374-18-2
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: 7-CHLORO-4-QUINAZOLINOL Visit Supplier Webpage Request for quotation
CAS: 31374-18-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 31374-18-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
7-CHLOROQUINAZOLIN-4-OL
R-2-[[[(1,1-diMethylethyl)diMethylsilyl]oxy]diphenylMethyl]-Pyrrolidine
BHB钾
Cycloheptanecarboxamide, N-[5-bromo-1-[(4-fluorophenyl)methyl]-1,2-dihydro-4-methyl-2-oxo-3-pyridinyl]-
3-氯-5-(三氟甲基)吡啶-2-乙酸
17β-Hydroxy-7α,17-diMethyl-androst-4-en-3-one
Cobalt disulfamate
4-Aminochromane-7-carboxylic acid hydrochloride
乙酰丙酮镱(III), REacton
N-ALPHA-BOC-L-ARGININE HYDROCHLORIDE SALT MONOHYDRATE
R-2-[[[(1,1-diMethylethyl)diMethylsilyl]oxy]diphenylMethyl]-Pyrrolidine
BHB钾
Cycloheptanecarboxamide, N-[5-bromo-1-[(4-fluorophenyl)methyl]-1,2-dihydro-4-methyl-2-oxo-3-pyridinyl]-
3-氯-5-(三氟甲基)吡啶-2-乙酸
17β-Hydroxy-7α,17-diMethyl-androst-4-en-3-one
Cobalt disulfamate
4-Aminochromane-7-carboxylic acid hydrochloride
乙酰丙酮镱(III), REacton
N-ALPHA-BOC-L-ARGININE HYDROCHLORIDE SALT MONOHYDRATE