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EGDME

1,2-Dimethoxyethane

CAS: 110-71-4

Molecular Formula: C4H10O2

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EGDME - Names and Identifiers

Name 1,2-Dimethoxyethane
Synonyms GDME
Glyme
EGDME
Monoglyme
Ansol E-121
ansulether121
dimethyl ether
CH3OCH2CH2OCH3
ansul ether 121
2,5-Dioxahexane
MONOETHYLENGLYCOL
1,2-dimethoxethane
Dimethylcollosolve
1,1-dimethoxyethane
1,2-dimethoxy-ethan
Dimethyl Cellosolve
1,2-Dimethoxyethane
Glycol dimethyl ether
ethylene dimethyl ether
dimethylcellosolvesolvent
alpha,beta-dimethoxyethane
1,2-ethanediol,dimethylether
Ethylene glycol dimethy ether
1,2-Ethanediol dimethyl ether
1,2-ethanediol, dimethyl ether
Ethylene glycol dimethyl ether
monoethylene glycol dimethyl ether
CAS 110-71-4
EINECS 203-794-9
InChI InChI=1/C4H10O2/c1-4(5-2)6-3/h4H,1-3H3
InChIKey XTHFKEDIFFGKHM-UHFFFAOYSA-N

EGDME - Physico-chemical Properties

Molecular FormulaC4H10O2
Molar Mass90.121
Density0.837g/cm3
Melting Point-69℃
Boling Point63°C at 760 mmHg
Flash Point32 °F
Water SolubilityMiscible
Solubility 1000g/l soluble
Vapor Presure187mmHg at 25°C
Vapor Density3.1 (20 °C, vs air)
AppearanceLiquid
ColorClear
Maximum wavelength(λmax)λ: 220 nm Amax: 1.00
λ: 250 nm Amax: 0.20
λ: 300 nm Amax: 0.03
λ: 350-400 nm Amax: 0.01
Merck14,3224
BRN1209237
Storage ConditionStore below +30°C.
StabilityStable, but explosive peroxides may form on exposure to air. Test for the presence of peroxides before heating. Avoid heat, light, air. Highly flammable. Store under inert gas.
SensitiveAir Sensitive
Explosive Limit10.4%
Refractive Index1.364
Physical and Chemical Properties

UseIt is mainly used in the field of polymer chemistry, Electrochemistry and boron chemical technology, and also used as a solvent for resins, nitrocellulose, etc., as well as a pharmaceutical extractant and an intermediate for organic synthesis.

EGDME - Risk and Safety

Hazard SymbolsF - Flammable
Flammable
T - Toxic
Toxic
Risk CodesR11 - Highly Flammable
R19 - May form explosive peroxides
R20 - Harmful by inhalation
R60 - May impair fertility
R61 - May cause harm to the unborn child
Safety DescriptionS45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S53 - Avoid exposure - obtain special instructions before use.
UN IDsUN 2252
WGK Germany1
RTECSKI1451000
FLUKA BRAND F CODES3-10-23
TSCAYes
Autoignition Temperature396 °F
HS Code29091900
Hazard Class3
Packing GroupII

EGDME - Upstream Downstream Industry

Raw MaterialsSodium hydroxide
2-Methoxyethanol
Downstream ProductsAzetidine
3-N-Boc-amino-azetidine
4-(Dicyanomethylene)-2-tert-butyl-6-(1,1,7,7-tetramethyljulolidin-4-yl-vinyl)-4H-pyran
Pigment Red 122
3-AMINOBIPHENYL
2-Aminoquinoline
TERT-BUTYL 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ISOINDOLINE-2-CARBOXYLATE
4-BENZYL-MORPHOLINE-2-CARBOXYLIC ACID
5-CHLORO-2'-DEOXYURIDINE
2-Chloro-5-cyano-3-methylpyridine
Quinacridone
N,N-DIPHENYLQUINACRIDONE
3,4-DICHLORO-N-METHYLANILINE
4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE
4'-BROMO-3'-FLUOROACETANILIDE
2-PHENYLMALONAMIDE
2-Bromo-5-hydroxypyridine radical ion(1+)
EUROPIUM D-3-TRIFLUOROACETYLCAMPHORATE
7-Methylthieno[3,2-d]pyrimidin-4(3H)-one
2-CHLORO-5-IODO-3-METHYLPYRIDINE
4-CHLORO-1,3-DIMETHYLPYRAZOLO[3,4-B]PYRIDINE-5-CARBOXYLIC ACID
1-METHYL-1H-INDOLE-5-BORONIC ACID 2,2-DIMETHYL PROPANE DIOL-1,3-CYCLIC ESTER
THIOPHENE-2,5-DICARBOXYLIC ACID MONOMETHYL ESTER
N,N'-Dimethylquinacridone
3-TRIFLUOROACETYL-D-CAMPHOR
10-UNDECYNOIC ACID
Tetrahydrocurcumin
TERT-BUTYL 4-(4-FORMYL-1,3-THIAZOL-2-YL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE
TERT-BUTYL 4-(5-FORMYL-4-METHYL-1,3-THIAZOL-2-YL)PIPERIDINE-1-CARBOXYLATE
Beraprost
TEMAFLOXACIN
Sarafloxacin
ETHYL 4-METHOXY-3-OXO-BUTANOATE
4-Thiazolecarboxylic acid
1,1,1-TRICHLOROACETONE
5-FORMYL-2-THIOPHENECARBOXYLIC ACID
2,3,5,6-Tetrafluorobenzyl alcohol
2,3,5,6-Tetrafluoro-4-methylbenzyl alcohol

EGDME - Security information

Category flammable liquids
Toxicity grading poisoning
The hazardous characteristics of flammability are flammable when exposed to open flames, high temperatures, and oxidants; combustion produces stimulating smoke
Storage and transportation characteristics The warehouse is ventilated and dry at low temperature; stored separately from the oxidant
Fire extinguishing agent dry powder, dry sand
Occupational standard STEL 10 mg/m3

Last Update：2024-04-10 22:29:15

EGDME - Uses and production methods

Uses are mainly used as solvents and organic synthesis intermediates
It is mainly used in the fields of polymer chemistry, electrochemistry and boron chemistry. It is also used as a solvent for resin, nitrocellulose, pharmaceutical extractant and organic synthesis intermediate.
The production method is obtained by reacting ethylene glycol monomethyl ether with metal sodium and methyl chloride. Refluxing ethylene glycol monomethyl ether with metal sodium until the metal sodium completely reacts, cooling to 45°C, and passing methyl chloride. After the reaction is completed, fractionation is carried out, and the 84-85.5 ℃ fraction is collected to obtain the finished product.

Last Update：2024-04-10 22:29:15

EGDME - Overview

Ethylene glycol dimethyl ether is also called 1, 2-dimethoxyethane, dimethyl cellosolve, α,β-dimethoxyethane, Glyme, or GDME for short. Colorless liquid. It smells of ether. Ethylene glycol dimethyl ether is an aprotic polar solvent with superior performance, which is widely used in chemical industry, pharmaceutical extractant and organic intermediate synthesis. Ethylene glycol dimethyl ether produced by traditional Williamson synthesis method is prepared under the action of sodium ethoxide phase transfer catalyst. Due to the long reaction path and many by-products, the process is difficult to separate products. In order to obtain pure products, it is necessary to neutralize waste lye through acid. The whole process will produce a large amount of industrial salt and wastewater, which causes serious environmental pollution, and the use of liquid acid and alkali has high requirements on the corrosion resistance of the equipment. With the need to upgrade products and the improvement of people's awareness of environmental protection, the use of environmentally friendly solid acid catalyst process has become an urgent need.

chemical properties colorless liquid. Melting point -58 ℃(-71 ℃), boiling point 84 ℃, relative density 0.8665(20/4 ℃), refractive index 1.3796, flash point 0 ℃. It is miscible with water and alcohol and soluble in hydrocarbon solvents. Has a strong ether-like smell.

Last Update：2024-04-10 22:29:15
Supplier List
JIANGSU BSECHEM CHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: 1,2-Dimethoxyethane Request for quotation
CAS: 110-71-4
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JIANGSU BSECHEM CHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: 1,2-Dimethoxyethane Request for quotation
CAS: 110-71-4
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685 Click to send a QQ messageSend QQ message
Nantong Reform Petro-Chemical CO., LTD.
Multiple SpecificationsSpot supply
Product Name: 1,2-Dimethoxyethane Request for quotation
CAS: 110-71-4
Tel: +86-17551318830
Email: r@reformchem.com­
Mobile: +86-17551318830
QQ: 3785839865 Click to send a QQ messageSend QQ message
Hubei YoungXin Pharmaceutical Tech Co.,Ltd.
Product Name: Glycerol Impurity 183 Request for quotation
CAS: 110-71-4
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052 Click to send a QQ message
Wechat: 15671228036
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: 1,2-Dimethoxyethane Request for quotation
CAS: 110-71-4
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: 1,2-Dimethoxyethane Request for quotation
CAS: 110-71-4
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
View History
EGDME
Raw Materials for EGDME
Sodium hydroxide
2-Methoxyethanol
Downstream Products for EGDME
4-(Dicyanomethylene)-2-tert-butyl-6-(1,1,7,7-tetramethyljulolidin-4-yl-vinyl)-4H-pyran
3-AMINOBIPHENYL
TERT-BUTYL 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ISOINDOLINE-2-CARBOXYLATE
4-BENZYL-MORPHOLINE-2-CARBOXYLIC ACID
5-CHLORO-2'-DEOXYURIDINE
2-Chloro-5-cyano-3-methylpyridine
Quinacridone
N,N-DIPHENYLQUINACRIDONE
3,4-DICHLORO-N-METHYLANILINE
4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE
4'-BROMO-3'-FLUOROACETANILIDE
1-METHYL-1H-INDOLE-5-BORONIC ACID 2,2-DIMETHYL PROPANE DIOL-1,3-CYCLIC ESTER
N,N'-Dimethylquinacridone
10-UNDECYNOIC ACID
TERT-BUTYL 4-(4-FORMYL-1,3-THIAZOL-2-YL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE
Sarafloxacin
ETHYL 4-METHOXY-3-OXO-BUTANOATE
1,1,1-TRICHLOROACETONE
2,3,5,6-Tetrafluoro-4-methylbenzyl alcohol
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