N-FMOC-1-氨基环丙烷羧酸

N-FMOC-1-氨基环丙烷羧酸 - Names and Identifiers

Name	FMOC-ACPC-OH
Synonyms	FMOC-AC3C-OH FMOC-ACPC-OH 1-(Fmoc-amino)cyclopropanecarboxylic acid 1-(FMOC-AMINO)-CYCLOPROPANECARBOXYLIC ACID 1-Aminocyclopropane-1-carboxylic acid, N-FMOC protected 1-(9-FLUORENYLMETHYLOXYCARBONYL-AMINO)-CYCLOPROPYL-1-CARBOXYLIC ACID 1-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}cyclopropanecarboxylic acid 1-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-1-cyclopropanecarboxylic acid 1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclopropane-1-carboxylic acid, (9H-Fluoren-9-yl)methyl (1-carboxycycloprop-1-yl)carbamate
CAS	116857-11-5 126705-22-4
InChI	InChI=1/C19H17NO4/c21-17(22)19(9-10-19)20-18(23)24-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2,(H,20,23)(H,21,22)

N-FMOC-1-氨基环丙烷羧酸 - Physico-chemical Properties

Molecular Formula	C19H17NO4
Molar Mass	323.34
Density	1.39±0.1 g/cm3(Predicted)
Melting Point	225-226
Boling Point	566.9±29.0 °C(Predicted)
Flash Point	296.7°C
Vapor Presure	1.09E-13mmHg at 25°C
Appearance	White powder
BRN	9348574
pKa	3.97±0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	1.671
MDL	MFCD00190873
Physical and Chemical Properties	Storage Conditions: 2-8 ℃ WGK Germany:3

N-FMOC-1-氨基环丙烷羧酸 - Risk and Safety

Hazard Symbols	Xi - Irritant
WGK Germany	3
Hazard Class	IRRITANT

N-FMOC-1-氨基环丙烷羧酸 - Introduction

1. nature:
1-(N-fluorenylmethoxycarbonylamino) cyclopropanecarboxylic acid is a white to gray solid with a special odor. It is stable at room temperature and soluble in organic solvents such as dimethylformamide (DMF), dichloromethane, etc.

2. use:
1-(N-fluorenylmethoxycarbonylamino) cyclopropanecarboxylic acid is a commonly used protecting group compound, which is often used to protect amino or hydroxyl groups in organic synthesis to prevent them from being affected by other reagents or reaction conditions. It is also commonly used in polymer synthesis, drug synthesis and other fields.

3. Preparation method:
The preparation of 1-(N-fluorenylmethoxycarbonylamino) cyclopropanecarboxylic acid generally employs a series of reaction steps. First, 1-(N-fluorenylmethyloxymethyl) ethylamine was obtained by the reaction of fluorenylmethanol with chloromethyl dimethylcarbamate by synthetic chemical methods. Then, 1-(N-fluorenylmethoxymethyl) ethylamine is reacted with cyclopropanecarboxylic acid by an etherification reaction to give the target product 1-(N-fluorenylmethoxycarbonylamino) cyclopropanecarboxylic acid.

4. Safety Information:
1-(N-fluorenylmethoxycarbonylamino) cyclopropanecarboxylic acid should be handled with caution to avoid contact with skin, eyes and respiratory tract. Always wear personal protective equipment such as lab gloves, goggles, and chemical shields during operation. If exposed, rinse immediately with plenty of water and seek medical assistance.

Last Update：2024-04-09 21:01:54

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