cyclocapron MedChemExpress (MCE)

Product Name	tranexamic acid
Synonyms	dv-79 amcha Amstat emorhalt cyclocapron cyklokapron tranexamic acid Synonyms dv-79 amcha Amstat emorhalt cyclocapron cyklokapron tranexamic acid TIMTEC-BB SBB006715 trans-cyclohexanecarboxylic acid 4-(aminomethyl)cyclohexanecarboxylic acid trans-4-Aminomethylcyclohexane-1-carboxylate trans-4-aminomethylcyclohexane-1-carboxylate TRANS-4-(AMINOMETHYL)CYCLOHEXANECARBOXYLIC ACID trans-4-(aminomethyl)cyclohexanecarboxylic acid TRANS-4-AMINOMETHYL-1-CYCLOHEXANECARBOXYLIC ACID trans-4-(Aminomethyl)cyclohexanecarboxylic acid
CAS	1197-18-8;701-54-2
EINECS	214-818-2
Chemical Formula	C8H15NO2
Molecular Weight	157.21
inchi	InChI=1/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-
Package	10 mM * 1 mL;500 mg;5 g;10 g
Price	Email to quote
Descriptions	Tranexamic acid Tranexamic acid MedChemExpress (MCE) HY-B0149 1197-18-8 cyclocapron 98.0% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions Tranexamic acid Tranexamic acid MedChemExpress (MCE) HY-B0149 1197-18-8 cyclocapron 98.0% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. Tranexamic acid (cyclocapron), a cyclic analog of lysine, is an orally active antifibrinolytic agent. Tranexamic acid attenuates the effects of severe trauma, inhibits urokinase plasminogen activator and ameliorates dry wrinkles. Tranexamic acid can used for the research of hemostasis . Tranexamic acid (20-100 μg/mL, 24 h) attenuates the effects of severe trauma by enhancing mitochondrial respiration, suppressing damage-associated molecular patterns (DAMPs) release and improving capillary integrity in human umbilical vein endothelial cells (HUVECs) and human arterial endothelial cells (HAECs)[1]. Tranexamic acid (0.2-5 mM, 30 min) inhibits cell migration of MDA-MB-231 BAG breast cancer cells[2]. Tranexamic acid (100 mg/kg, Intravenous injection, twice a day for 3-28 days) facilitates a more robust immune activation after traumatic brain injury in plasminogen-deficient mice[3]. Tranexamic acid (750 mg/kg, Oral, once a day for 20 consecutive days) decreases the proliferation of mast cells and increases the proliferation of fibroblasts, subsequently improving wrinkles caused by skin dryness in mice[4]. MMP-1 \| \| \| \| \| \| \| \| \| \| [1]. Prudovsky I, et al. Tranexamic acid suppresses the release of mitochondrial DNA, protects the endothelial monolayer and enhances oxidative phosphorylation [J]. Journal of cellular physiology, 2019, 234(11): 19121-19129. [Content Brief] [2]. Wu G, et al. Tranexamic acid is an active site inhibitor of urokinase plasminogen activator [J]. Blood advances, 2019, 3(5): 729-733. [Content Brief] [3]. Draxler D F, et al. Tranexamic acid modulates the cellular immune profile after traumatic brain injury in mice without hyperfibrinolysis [J]. Journal of Thrombosis and Haemostasis, 2019, 17(12): 2174-2187. [Content Brief] [4]. Hiramoto K, et al. The amelioration effect of tranexamic acid in wrinkles induced by skin dryness [J]. Biomedicine & Pharmacotherapy, 2016, 80: 16-22. [Content Brief] [5]. Sindet-Pedersen S, et al. Hemostatic effect of tranexamic acid mouthwash in anticoagulant-treated patients undergoing oral surgery [J]. New England Journal of Medicine, 1989, 320(13): 840-843. [Content Brief]
Supplier Website	https://www.medchemexpress.com/Tranexamic-acid.html
Last Update	2025-05-21 16:50:25

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