YL-109 MedChemExpress (MCE)

Product Name	2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE
Synonyms	Y109 Y-109 YL-109 4-(benzo[d]thiazol-2-yl)-2-Methoxyphenol 4-(1,3-Benzothiazol-2-yl)-2-methoxyphenol 2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE 4-(3H-1,3-benzothiazol-2-ylidene)-2-methoxycyclohexa-2,5-dien-1-one
CAS	36341-25-0
EINECS
Chemical Formula	C14H11NO2S
Molecular Weight	257.31
inchi
Package	10 mM * 1 mL;5 mg;10 mg;25 mg;50 mg;100 mg
Price	Email to quote
Descriptions	YL-109 YL-109 MedChemExpress (MCE) HY-18619 36341-25-0 99.26% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions YL-109 YL-109 MedChemExpress (MCE) HY-18619 36341-25-0 99.26% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. YL-109 is an antitumor agent that can induce carboxyl terminus of Hsp70-interacting protein (CHIP) expression through aryl hydrocarbon receptor (AhR) signaling. YL-109 has ability to inhibit breast cancer cell growth and invasiveness. YL-109 (0.001-10 μM 96 h or 24 h) inhibits cell proliferation, motility, and invasiveness in breast cancer cells[1]. YL-109 (1 μM) increases both CHIP mRNA and protein levels in MDA-MB-231 cells[1]. YL-109 (15 mg/kg s.c. for every 2 d) inhibits both tumor growth and cancer metastasis of breast cancer cells in vivo[1]. \| \| \| \| \| \| \| \| \| \| [1]. Hiyoshi H, et al. 2-(4-Hydroxy-3-methoxyphenyl)-benzothiazole suppresses tumor progression and metastatic potential of breast cancer cells by inducing ubiquitin ligase CHIP. Sci Rep. 2014 Nov 18 4:7095. [Content Brief]
Last Update	2025-04-01 14:45:47

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