Isoxazole 9 MedChemExpress (MCE)

Product Name	N-Cyclopropyl-5-(thiophen-2-yl)isoxazole-3-carboxamide
Synonyms	ISX 9 Isoxazole 9 Isoxazole(ISX-9) ISX 9(Isoxazole 9) ISX-9 (Isoxazole 9) Neuronal Differentiation Inducer III 3-IsoxazolecarboxaMide, N-cyclopropyl-5-(2-thienyl)- Synonyms ISX 9 Isoxazole 9 Isoxazole(ISX-9) ISX 9(Isoxazole 9) ISX-9 (Isoxazole 9) Neuronal Differentiation Inducer III 3-IsoxazolecarboxaMide, N-cyclopropyl-5-(2-thienyl)- N-Cyclopropyl-5-(2-thienyl)-1,2-oxazole-3-carboxamide N-Cyclopropyl-5-(thiophen-2-yl)isoxazole-3-carboxaMide N-Cyclopropyl-5-(thiophen-2-yl)isoxazole-3-carboxamide
CAS	832115-62-5
EINECS
Chemical Formula	C11H10N2O2S
Molecular Weight	234.27
inchi
Package	10 mM * 1 mL;10 mM * 1 mL;1 mg;1 mg;5 mg;5 mg;10 mg;10 mg;50 mg;50 mg
Price	Email to quote
Descriptions	ISX-9 ISX-9 MedChemExpress (MCE) HY-12323 832115-62-5 Isoxazole 9 99.19% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions ISX-9 ISX-9 MedChemExpress (MCE) HY-12323 832115-62-5 Isoxazole 9 99.19% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. ISX-9 (Isoxazole 9) is a potent inducer of adult neural stem cell differentiation. ISX-9 activates Ca2+ influx through both voltage-gated Ca2+ channels and NMDA receptors and increases neuroD expression. ISX-9 also induces cardiomyogenic differentiation of Notch-activated epicardium-derived cells (NECs). ISX-9 (20 mg/kg for 12 days mice) treatment improves hippocampal function. ISX-9 enhances spatial memory ability in the Morris water maze test. ISX-9 enhances hippocampal neurogenesis and memory in vivo, and its effects are reliant on Mef2[1]. \| \| \| \| \| \| \| \| \| \| [1]. Petrik D, et al. Functional and mechanistic exploration of an adult neurogenesis-promoting small molecule. FASEB J. 2012 Aug 26(8):3148-3162. [Content Brief] [2]. Jay W Schneider, et al. Small-molecule activation of neuronal cell fate. Nat Chem Biol. 2008 Jul 4(7):408-10. [Content Brief] [3]. Jamie L Russell, et al. Targeting native adult heart progenitors with cardiogenic small molecules. ACS Chem Biol. 2012 Jun 15 7(6):1067-76. [Content Brief]
Supplier Website	https://www.medchemexpress.com/ISX-9.html
Last Update	2025-05-21 16:50:25

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