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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product NameAlizarin violet
SynonymsAlizarin violet
CAS2103-64-2
EINECS
Chemical FormulaC20H12O7
Molecular Weight364.3
inchi
Package10 mM * 1 mL;5 mg;10 mg
PriceEmail to quote
DescriptionsGallein

Gallein

MedChemExpress (MCE)

HY-D0254

2103-64-2

Pyrogallol phthalein

98.0%

4°C, protect from light *In solvent : -80°C, 6 months

Descriptions

Gallein

Gallein

MedChemExpress (MCE)

HY-D0254

2103-64-2

Pyrogallol phthalein

98.0%

4°C, protect from light *In solvent : -80°C, 6 months
-20°C, 1 month (protect from light)

Room temperature in continental US
may vary elsewhere.

Gallein is a Gβγ subunit signaling inhibitor that can interfere with the interaction between Gβγ subunit and PI3Kγ, regulate platelet function, and exhibit anti-tumor activity[1][3].

Gallein (10 μM, 0-150 h) inhibits β-ionone induced cell invasion in LNCaP prostate cancer cells[1]. Gallein (30 μM, 1 h) increases osteoprotegerin (OPG) synthesis induced by fibroblast growth factor 2 (FGF-2) in osteoblasts[2]. Gallein (25-50 μM, 24 h) inhibits platelet aggregation, secretion, and diffusion functions[3].

Gallein (5 mg/kg, 15 days, i.p.) inhibits tumor cell proliferation in male NSG mice[1]. Gallein (20 mg/kg, b.i.d, i.v.) regulates hemostasis and prevents arterial thrombosis in C57BL/6 mice[3].

Gβγ subunit In Vitro Gallein (10 μM, 0-150 h) inhibits β-ionone induced cell invasion in LNCaP prostate cancer cells[1]. Gallein (30 μM, 1 h) increases osteoprotegerin (OPG) synthesis induced by fibroblast growth factor 2 (FGF-2) in osteoblasts[2]. Gallein (25-50 μM, 24 h) inhibits platelet aggregation, secretion, and diffusion functions[3]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Gallein Related Antibodies Cell Invasion Assay[1]. Cell Line: LNCaP cell

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[1]. Sanz G, et al, Gallein, a Gβγ subunit signalling inhibitor, inhibits metastatic spread of tumour cells expressing OR51E2 and exposed to its odorant ligand. BMC Res Notes. 2017 Oct 30
10(1):541.

[2]. Kuroyanagi G, Hioki T, Matsushima-Nishiwaki R, Kozawa O, Tokuda H. Gallein increases the fibroblast growth factor 2-elicited osteoprotegerin synthesis in osteoblasts. Biochim Biophys Acta Gen Subj. 2024 Aug
1868(8):130635.
[Content Brief]

[3]. Alarabi AB, et al. The G-protein βγ subunits regulate platelet function. Life Sci. 2020 Dec 1
262:118481.
[Content Brief]

Supplier Websitehttps://www.medchemexpress.com/gallein.html
Last Update2025-05-21 16:50:25
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