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AA-861

docebenone

CAS: 80809-81-0

Molecular Formula: C21H26O3

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AA-861 - Names and Identifiers

Name docebenone
Synonyms AA-861
AA 861
A 61589
Decebenone
Docebenona
Docebenone
docebenone
Docebenonum
UNII-2XRX3BD53M
AA-861(Docebenone)
Docebenonum [INN-Latin]
Docebenona [INN-Spanish]
2-(12-Hydroxy-5,10-dodecadiynyl)-3,5,6-trimethyl-p-benzoquinone
2-[12-HYDROXYDODECA-5,10-DIYNYL]-3,5,6-TRIMETHYL-P-BENZOQUINONE
2-(12-Hydroxydodecane-5,10-diynyl)-3,5,6-trimethyl-p-benzoquinone
2-(12-hydroxydodeca-5,10-diynyl)-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione
2-(12-Hydroxy-5,10-dodecadiynyl)-3,5,6-trimethyl-2,5-cyclohexadiene-1,4-dione
2,5-Cyclohexadiene-1,4-dione, 2-(12-hydroxy-5,10-dodecadiynyl)-3,5,6-trimethyl-
2-(12-hydroxydodeca-5,10-diyn-1-yl)-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione
CAS 80809-81-0
InChI InChI=1/C21H26O3/c1-16-17(2)21(24)19(18(3)20(16)23)14-12-10-8-6-4-5-7-9-11-13-15-22/h22H,5,7-10,12,14-15H2,1-3H3

AA-861 - Physico-chemical Properties

Molecular FormulaC21H26O3
Molar Mass326.43
Density1.071g/cm3
Boling Point488.5°C at 760 mmHg
Flash Point263.3°C
Solubility ethanol:
Vapor Presure1.36E-11mmHg at 25°C
Storage Condition2-8°C
Refractive Index1.532
In vitro study Treatment of trichomonads with the 5-LO inhibitor Docebenone, significantly inhibits the ability of trichomonads to secrete LTB 4 compared to results for trichomonads treated with medium. Docebenone strongly abolishes the stimulatory effect of TvSP on IL-8 production. Docebenone at 10-200 μM increases [Ca 2+ ] i concentration dependently.
In vivo study Docebenone might protect experimental acute necrotizing pancreatitis in rats. Docebenone suppresses the release of SRS-A by 55-97%, dose-dependently in doses of 10 -8 -10 -5 M in monkeys. The antigen-induced SRS-A release from these fragments is dose dependently inhibited by 25-93% of Docebenone, with doses of 10 -8 -10 -5 M.

AA-861 - Risk and Safety

Hazard SymbolsXi - Irritant
Irritant
Risk Codes36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
WGK Germany3

AA-861 - Reference Information

biological activity Docebenone (AA 861) is a potent, selective and orally active 5-lipoxygenase (5-LO) inhibitors.
Last Update:2024-04-09 15:16:53
AA-861
Supplier List
MedChemExpress (MCE)
Spot supply
Product Name: AA 861 Visit Supplier Webpage Request for quotation
CAS: 80809-81-0
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
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CAS: 80809-81-0
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Shanghai Macklin Biochemical Co., Ltd
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CAS: 80809-81-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
MedChemExpress (MCE)
Spot supply
Product Name: AA 861 Visit Supplier Webpage Request for quotation
CAS: 80809-81-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Docebenone Visit Supplier Webpage Request for quotation
CAS: 80809-81-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: Docebenone Visit Supplier Webpage Request for quotation
CAS: 80809-81-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
View History
AA-861
4-Heptylphenol
4-AMINOTOLUENE-2-SULFONANILIDE
Fitc
Bisphenol A Bis(2,3-dihydroxypropyl) Ether
Diethyl thiophosphoric chloride
Azmacort-13C3
FMOC-D-PHG-OH
10341-03-4
mitsui crystal violet
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