Docebenona
docebenone
CAS: 80809-81-0
Molecular Formula: C21H26O3
Docebenona - Names and Identifiers
Docebenona - Physico-chemical Properties
| Molecular Formula | C21H26O3 |
| Molar Mass | 326.43 |
| Density | 1.071g/cm3 |
| Boling Point | 488.5°C at 760 mmHg |
| Flash Point | 263.3°C |
| Solubility | ethanol: |
| Vapor Presure | 1.36E-11mmHg at 25°C |
| Storage Condition | 2-8°C |
| Refractive Index | 1.532 |
| In vitro study | Treatment of trichomonads with the 5-LO inhibitor Docebenone, significantly inhibits the ability of trichomonads to secrete LTB 4 compared to results for trichomonads treated with medium. Docebenone strongly abolishes the stimulatory effect of TvSP on IL-8 production. Docebenone at 10-200 μM increases [Ca 2+ ] i concentration dependently. |
| In vivo study | Docebenone might protect experimental acute necrotizing pancreatitis in rats. Docebenone suppresses the release of SRS-A by 55-97%, dose-dependently in doses of 10 -8 -10 -5 M in monkeys. The antigen-induced SRS-A release from these fragments is dose dependently inhibited by 25-93% of Docebenone, with doses of 10 -8 -10 -5 M. |
Docebenona - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
Docebenona - Reference Information
| biological activity | Docebenone (AA 861) is a potent, selective and orally active 5-lipoxygenase (5-LO) inhibitors. |
Last Update：2024-04-09 15:16:53
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Spot supply
Product Name: AA 861 Visit Supplier Webpage Request for quotationCAS: 80809-81-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Docebenone Visit Supplier Webpage Request for quotationCAS: 80809-81-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Docebenone Visit Supplier Webpage Request for quotationCAS: 80809-81-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
View History
Docebenona
[2,4'-Bipyridine]-1'(2'H)-carboxylic acid, 6-chloro-3',6'-dihydro-, 1,1-dimethylethyl ester
乙二醇硬脂酸酯 SE
tert-butyl (2-(4-methylpiperidin-4-yl)ethyl)carbamate oxalate
泊马度胺杂质5
THIAZOLE-5-METHANOL
4-N-叔丁氧羰基-哌嗪-2-羧酸
多索茶碱杂质36
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-3-methyl-, hydrochloride (1:1)
3-(4-甲基苯亚甲基)樟脑
[2,4'-Bipyridine]-1'(2'H)-carboxylic acid, 6-chloro-3',6'-dihydro-, 1,1-dimethylethyl ester
乙二醇硬脂酸酯 SE
tert-butyl (2-(4-methylpiperidin-4-yl)ethyl)carbamate oxalate
泊马度胺杂质5
THIAZOLE-5-METHANOL
4-N-叔丁氧羰基-哌嗪-2-羧酸
多索茶碱杂质36
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-3-methyl-, hydrochloride (1:1)
3-(4-甲基苯亚甲基)樟脑